MAST1 and IFIT5

Data Source:
BioGRID (two hybrid)

		MAST1	IFIT5
Description		microtubule associated serine/threonine kinase 1	interferon induced protein with tetratricopeptide repeats 5
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body	Cytosol Plasma Membrane IkappaB Kinase Complex Actin Cytoskeleton Ruffle Membrane Apical Part Of Cell
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus
Pathways			Interferon alpha/beta signaling
Drugs		Fostamatinib
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		40 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH HSP90AB1 IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 UBE2D3	17 interacting genes: A2M APOE CDC37 CHUK ECSIT IFIT1 IFIT3 IKBKG LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2
Entrez ID		22983	24138
HPRD ID		17469	17130
Ensembl ID		ENSG00000105613	ENSG00000152778
Uniprot IDs		Q9Y2H9	Q13325
PDB IDs		2M9X 3PS4	3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U
Enriched GO Terms of Interacting Partners?
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