RAB3D and RPH3AL

Data Source:
HPRD (in vivo, in vitro)

		RAB3D	RPH3AL
Description		RAB3D, member RAS oncogene family	rabphilin 3A like (without C2 domains)
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding	Protein Binding Cytoskeletal Protein Binding LIM Domain Binding Metal Ion Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Neutrophil Degranulation Bone Resorption Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway	Intracellular Protein Transport Exocytosis Regulation Of Exocytosis Response To Drug Positive Regulation Of Protein Secretion
Pathways		Neutrophil degranulation RAB geranylgeranylation
Drugs
Diseases
GWAS		Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)	AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)
Interacting Genes		15 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF RIMS2 RNF32 RPH3AL SYTL4 VRTN	25 interacting genes: ANKRD11 ATPAF2 C1orf109 HNRNPK KHDRBS3 MID2 MYO15B PNMA3 PRKAB2 PSME3 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 RSPH14 SAAL1 SCNM1 TCEA3 UNC13B ZYX
Entrez ID		9545	9501
HPRD ID		05070	05345
Ensembl ID		ENSG00000105514	ENSG00000181031
Uniprot IDs		A0A024R7G2 O95716	A8K7D5 Q9UNE2
PDB IDs		2GF9
Enriched GO Terms of Interacting Partners?
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