RAB3D and RAB3IP

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		RAB3D	RAB3IP
Description		RAB3D, member RAS oncogene family	RAB3A interacting protein
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GO Annotations	Cellular Component	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle	Nucleus Cytosol Cytoskeleton Lamellipodium Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Neutrophil Degranulation Bone Resorption Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway	Protein Targeting To Membrane Exocytosis Regulation Of Catalytic Activity Ciliary Basal Body-plasma Membrane Docking
Pathways		Neutrophil degranulation RAB geranylgeranylation	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		15 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF RIMS2 RNF32 RPH3AL SYTL4 VRTN	32 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76
Entrez ID		9545	117177
HPRD ID		05070	10565
Ensembl ID		ENSG00000105514	ENSG00000127328
Uniprot IDs		A0A024R7G2 O95716	Q96QF0
PDB IDs		2GF9	4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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