RAB3D and SYTL4

Data Source:
BioGRID (two hybrid)

		RAB3D	SYTL4
Description		RAB3D, member RAS oncogene family	synaptotagmin like 4
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GO Annotations	Cellular Component	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle	Endosome Plasma Membrane Extrinsic Component Of Membrane Transport Vesicle Membrane Platelet Alpha Granule Membrane Exocytic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding	Protein Binding Phospholipid Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Neutrophil Degranulation Bone Resorption Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway	Plasma Membrane Repair Platelet Degranulation Intracellular Protein Transport Exocytosis Lysosome Localization Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway Regulation Of Plasma Membrane Repair
Pathways		Neutrophil degranulation RAB geranylgeranylation	Platelet degranulation
Drugs			Insulin pork
Diseases
GWAS		Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)	Lean body mass ( 28552196) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		15 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF RIMS2 RNF32 RPH3AL SYTL4 VRTN	27 interacting genes: CCDC85B CEP70 DVL3 FCHO1 FXR2 HMG20A INS KIFC3 LMO1 LZTS1 OSBPL3 PRKAR1B RAB27A RAB27B RAB3A RAB3D RAB8A ROPN1 SPANXN2 STX1A STXBP1 TBC1D1 TRIM37 TRIM41 ZBTB7B ZBTB9 ZRANB1
Entrez ID		9545	94121
HPRD ID		05070	06735
Ensembl ID		ENSG00000105514	ENSG00000102362
Uniprot IDs		A0A024R7G2 O95716	A0A024RCF8 A8K973 B2R7R4 Q71SF7 Q96C24
PDB IDs		2GF9	2CSZ 3FDW 5X6T
Enriched GO Terms of Interacting Partners?
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