SIL1 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide
Novel	GHRL	ghrelin and obestatin prepropeptide
Novel	NPM1	nucleophosmin 1	Nuclear import of Rev protein Nuclear import of Rev protein SUMOylation of transcription cofactors Deposition of new CENPA-containing nucleosomes at the centromere TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation SARS-CoV-1-host interactions ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants Nuclear events stimulated by ALK signaling in cancer PKR-mediated signaling	Artenimol
Novel	PCDHB16	protocadherin beta 16
Novel	RFK	riboflavin kinase	Vitamin B2 (riboflavin) metabolism	Riboflavin Flavin mononucleotide
Novel	SETD7	SET domain containing 7, histone lysine methyltransferase	PKMTs methylate histone lysines	S-adenosyl-L-homocysteine
	CCND3	cyclin D3	Transcriptional regulation of white adipocyte differentiation MAPK6/MAPK4 signaling Cyclin D associated events in G1 Regulation of RUNX1 Expression and Activity Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Drug-mediated inhibition of CDK4/CDK6 activity
	FEM1C	fem-1 homolog C	Neddylation
	HSPA5	heat shock protein family A (Hsp70) member 5	Platelet degranulation Regulation of HSF1-mediated heat shock response ATF6 (ATF6-alpha) activates chaperones PERK regulates gene expression IRE1alpha activates chaperones ATF6 (ATF6-alpha) activates chaperone genes ATF6B (ATF6-beta) activates chaperones Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC Modulation of host responses by IFN-stimulated genes	Antihemophilic factor, human recombinant Acetylsalicylic acid Copper Lonoctocog alfa Moroctocog alfa
	SGTB	small glutamine rich tetratricopeptide repeat co-chaperone beta
	SMAD9	SMAD family member 9	Signaling by BMP
	UBQLN1	ubiquilin 1	Cargo recognition for clathrin-mediated endocytosis

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