Search Results for: FDX1

12 interactions involving FDX1 - ferredoxin 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel BIRC2 baculoviral IAP repeat containing 2
  • Apoptotic cleavage of cellular proteins
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIPK1-mediated regulated necrosis
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR2 non-canonical NF-kB pathway
  • Regulation of necroptotic cell death
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ub-specific processing proteases
  • IKK complex recruitment mediated by RIP1
Novel BIRC3 baculoviral IAP repeat containing 3
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIPK1-mediated regulated necrosis
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR2 non-canonical NF-kB pathway
  • Regulation of necroptotic cell death
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ub-specific processing proteases
  • IKK complex recruitment mediated by RIP1
Novel CNTN5 contactin 5
  • Post-translational modification: synthesis of GPI-anchored proteins
Novel CORO2A coronin 2A
Novel LILRB2 leukocyte immunoglobulin like receptor B2
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Neutrophil degranulation
Novel PBRM1 polybromo 1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Formation of the polybromo-BAF (pBAF) complex
Novel RDH5 retinol dehydrogenase 5
  • The canonical retinoid cycle in rods (twilight vision)
  • RA biosynthesis pathway
  • Defective visual phototransduction due to RDH5 loss of function
  • NADH
  • Vitamin A
  • Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
CYCS cytochrome c, somatic
  • Release of apoptotic factors from the mitochondria
  • Formation of apoptosome
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • Transcriptional activation of mitochondrial biogenesis
  • Detoxification of Reactive Oxygen Species
  • Pyroptosis
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Regulation of the apoptosome activity
  • Regulation of the apoptosome activity
  • Cytoprotection by HMOX1
  • Minocycline
  • Protoporphyrin Ix Containing Co
  • Ferroheme C
  • Imidazole
  • Zinc protoporphyrin
  • Trimethyllysine
  • Zinc Substituted Heme C
  • Artenimol
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
CYP11A1 cytochrome P450 family 11 subfamily A member 1
  • Pregnenolone biosynthesis
  • Endogenous sterols
  • Defective CYP11A1 causes AICSR
  • Aminoglutethimide
  • Levoketoconazole
  • Congenital adrenal hyperplasia (CAH)
  • 46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
CYP11B2 cytochrome P450 family 11 subfamily B member 2
  • Mineralocorticoid biosynthesis
  • Glucocorticoid biosynthesis
  • Endogenous sterols
  • Defective CYP11B2 causes CMO-1 deficiency
  • Spironolactone
  • Levoketoconazole
  • Osilodrostat
  • Aldosterone synthase deficiency; Corticosterone methyloxidase type I deficiency; Corticosterone methyloxidase type II deficiency
  • Glucocorticoid-remediable aldosteronism (GRA)
FDXR ferredoxin reductase
  • Pregnenolone biosynthesis
  • Endogenous sterols
  • Electron transport from NADPH to Ferredoxin
  • Defective CYP11A1 causes AICSR
  • Flavin adenine dinucleotide
  • Nicotinamide adenine dinucleotide phosphate
PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Macroautophagy
  • AMPK inhibits chREBP transcriptional activation activity
  • AMPK inhibits chREBP transcriptional activation activity
  • Carnitine shuttle
  • Activation of PPARGC1A (PGC-1alpha) by phosphorylation
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • Regulation of TP53 Activity through Phosphorylation
  • Lipophagy
  • Activation of AMPK downstream of NMDARs
  • AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
  • Adenosine phosphate
  • Acetylsalicylic acid
  • Fostamatinib

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