Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
FDX1
Gene Name
ferredoxin 1
Image
Gene Ontology Annotations
Cellular Component
Mitochondrion
Mitochondrial Matrix
Molecular Function
Iron Ion Binding
Electron Carrier Activity
2 Iron, 2 Sulfur Cluster Binding
Biological Process
C21-steroid Hormone Biosynthetic Process
Xenobiotic Metabolic Process
Steroid Metabolic Process
Cholesterol Metabolic Process
Sterol Metabolic Process
Hormone Biosynthetic Process
Small Molecule Metabolic Process
Oxidation-reduction Process
Pathways
Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)
Metabolism of lipids and lipoproteins
Pregnenolone biosynthesis
Mitochondrial iron-sulfur cluster biogenesis
Metabolic disorders of biological oxidation enzymes
Phase 1 - Functionalization of compounds
Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)
Electron transport from NADPH to Ferredoxin
Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)
Cytochrome P450 - arranged by substrate type
Endogenous sterols
Biological oxidations
Defective FMO3 causes Trimethylaminuria (TMAU)
Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)
Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)
Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)
Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)
Defective CYP1B1 causes Glaucoma
Metabolism of steroid hormones and vitamin D
Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)
Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)
Defective CYP19A1 causes Aromatase excess syndrome (AEXS)
Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)
Defective MAOA causes Brunner syndrome (BRUNS)
Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)
Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)
Drugs
Mitotane
Diseases
GWAS
Protein-protein Interactions
5 interactors:
CYCS
CYP11A1
CYP11B2
FDXR
PRKAB2
Entrez ID
2230
HPRD ID
00059
Ensembl ID
ENSG00000137714
Uniprot IDs
P10109
PDB IDs
3N9Y
3N9Z
3NA0
3NA1
3P1M
Enriched GO Terms of Interacting Partners
?
C21-steroid Hormone Biosynthetic Process
C21-steroid Hormone Metabolic Process
Hormone Biosynthetic Process
Cellular Ketone Metabolic Process
Steroid Biosynthetic Process
Oxidation-reduction Process
Lipid Biosynthetic Process
Sterol Metabolic Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Response To Xenobiotic Stimulus
Hormone Metabolic Process
Small Molecule Metabolic Process
Steroid Metabolic Process
Regulation Of Hormone Levels
Alcohol Metabolic Process
Lipid Metabolic Process
Generation Of Precursor Metabolites And Energy
Cellular Response To Hormone Stimulus
Cholesterol Metabolic Process
Cellular Response To Metal Ion
Cellular Response To Inorganic Substance
Response To Genistein
Regulation Of Blood Volume By Renal Aldosterone
Response To Hormone
Granulosa Cell Differentiation
Aldosterone Biosynthetic Process
Cortisol Biosynthetic Process
Fractalkine Metabolic Process
Response To Reactive Oxygen Species
Mitochondrial Electron Transport, Cytochrome C To Oxygen
Response To Fungicide
Chemokine Metabolic Process
Testosterone Biosynthetic Process
Response To Hydroxyisoflavone
Mineralocorticoid Biosynthetic Process
Cellular Response To Potassium Ion
Phthalate Metabolic Process
Dibenzo-p-dioxin Metabolic Process
Energy Derivation By Oxidation Of Organic Compounds
Cellular Response To Peptide Hormone Stimulus
Biphenyl Metabolic Process
Mitochondrial Electron Transport, Ubiquinol To Cytochrome C
Carnitine Shuttle
Cellular Response To Stimulus
Cellular Response To Peptide
Response To Metal Ion
Response To Potassium Ion
Glucocorticoid Biosynthetic Process
Response To L-ascorbic Acid
Tagcloud
?