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PLEKHN1

Name pleckstrin homology domain containing N1
Structure No pdb structure
Novel Interactors 1 novel interactors: PUSL1
Interactors 42 interactors: ABI2 AKAP8L ARID5A ATXN1 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PRICKLE4 PRKAA2 REL RFX6 SAXO4 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1
GO Annotations Cellular Component
  • Mitochondrion
  • Cytosol
  • Cytoskeleton
  • Plasma Membrane
  • Membrane
  • Mitochondrial Membrane
Molecular Function
  • Phosphatidylserine Binding
  • Protein Binding
  • Phosphatidic Acid Binding
  • Cardiolipin Binding
  • Phosphatidylinositol Phosphate Binding
Biological Process
  • Response To Hypoxia
  • Positive Regulation Of Apoptotic Process
  • 3'-UTR-mediated MRNA Destabilization
GWAS
  • Height ( 31562340 )
  • Parkinson's disease ( 26227905 )
Entrez ID 84069
HPRD ID 13190
Ensembl ID ENSG00000187583
Uniprot IDs Q494U1
PDB IDs Not available
GO Terms Enriched among Interactors ?
  • Intermediate Filament
  • Structural Constituent Of Skin Epidermis
  • Keratin Filament

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