DMTF1 and ATF7IP

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
HPRD (two hybrid)

		DMTF1	ATF7IP
Description		cyclin D binding myb like transcription factor 1	activating transcription factor 7 interacting protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding ATP Hydrolysis Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways			PKMTs methylate histone lysines Regulation of endogenous retroelements by KRAB-ZFP proteins Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Drugs
Diseases
GWAS		Bipolar disorder or major depressive disorder ( 20351715) Brachial circumference ( 22479309) Schizophrenia ( 28991256 29483656 30285260)	Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340 33713608) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Leukocyte telomere length ( 32109421) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240 28604728 28604732)
Interacting Genes		9 interacting genes: ATF7IP CCND1 CCND2 CCND3 DNMT3L KPNA4 MTDH SRA1 TP53	71 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EHMT2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HMGB1 HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		9988	55729
HPRD ID		09770	09811
Ensembl ID		ENSG00000135164	ENSG00000171681
Uniprot IDs		B3KMJ8 Q9Y222	B3KNI7 B3KQF8 Q6VMQ6
PDB IDs		2LLK	2RPQ
Enriched GO Terms of Interacting Partners?		Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Response To X-ray Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Kinase Holoenzyme Complex Positive Regulation Of Cell Cycle G1/S Phase Transition Protein Serine/threonine Kinase Activator Activity Nuclear Membrane Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Microtubule Organizing Center Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of RNA Metabolic Process Positive Regulation Of Cell Cycle Phase Transition Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Nucleobase-containing Compound Metabolic Process Mitotic G1/S Transition Checkpoint Signaling Positive Regulation Of Mitotic Cell Cycle Response To Ionizing Radiation Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Nucleus DNA Methylation-dependent Constitutive Heterochromatin Formation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cell Cycle Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Epigenetic Regulation Of Gene Expression Regulation Of Cell Cycle Process Constitutive Heterochromatin Formation Transcription Repressor Complex Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition Mitotic DNA Damage Checkpoint Signaling Positive Regulation Of Cell Cycle Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Negative Regulation Of Macromolecule Metabolic Process	Transcription By RNA Polymerase II DNA-templated Transcription Morphogenesis Of A Polarized Epithelium Transcription Initiation At RNA Polymerase II Promoter Nucleoplasm DNA-templated Transcription Initiation Basement Membrane Laminin-11 Complex Laminin-10 Complex Lymph Vessel Morphogenesis RNA Polymerase II, Core Complex Nucleobase-containing Compound Biosynthetic Process SUMO Transferase Activity Regulation Of Transepithelial Transport Dense Body Regulation Of Multicellular Organismal Development Nuclear Thyroid Hormone Receptor Binding Presynaptic Cytosol Macromolecule Biosynthetic Process Postsynaptic Cytosol Structural Constituent Of Postsynaptic Actin Cytoskeleton Maintenance Of Blood-brain Barrier Proximal Tubule Development Focal Adhesion DNA-directed RNA Polymerase Complex Golgi To Plasma Membrane Protein Transport Histone H3K9me2 Methyltransferase Activity DNA Methylation-dependent Constitutive Heterochromatin Formation Extracellular Exosome Positive Regulation Of Endothelial Cell Proliferation Regulation Of Transcription By RNA Polymerase II Histone H3K9 Methyltransferase Activity Nucleus
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