DMTF1 and CCND2

Number of citations of the paper that reports this interaction (PMID 8887674)
35

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		DMTF1	CCND2
Gene Name		cyclin D binding myb-like transcription factor 1	cyclin D2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Cyclin-dependent Protein Kinase Holoenzyme Complex Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Membrane
	Molecular Function	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity	Protein Binding Protein Kinase Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle	Positive Regulation Of Protein Phosphorylation Cell Cycle Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division
Pathways			Cyclin D associated events in G1 G1 Phase Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Bipolar disorder and major depressive disorder (combined) ( 20351715) Brachial circumference ( 22479309)	Colorectal cancer ( 23266556 23263487) Major depressive disorder ( 19107115 23377640) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443) Red blood cell count ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		5 interactors: ATF7IP CCND1 CCND2 CCND3 SRA1	19 interactors: ABL1 AKAP8 CALM1 CALM2 CALM3 CDK4 CDK5 CDKN1A CDKN1B CDKN2A DMTF1 FBXL2 HIST1H1A NPDC1 PCGF2 PSMD10 RB1 RUNX1 SERTAD1
Entrez ID		9988	894
HPRD ID		09770	00451
Ensembl ID		ENSG00000135164	ENSG00000118971
Uniprot IDs		B3KMJ8 Q9Y222	P30279
PDB IDs		2LLK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Cycle Cell Division Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Protein Phosphorylation Cell Proliferation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Regulation Of Cell Cycle Re-entry Into Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Response To UV-A Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Phosphorylation Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Metabolic Process Regulation Of Mammary Gland Epithelial Cell Proliferation Response To Magnesium Ion Response To Vitamin E Leydig Cell Differentiation Mammary Gland Epithelial Cell Proliferation Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Cell Cycle Arrest Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To X-ray Regulation Of Protein Metabolic Process Response To Corticosterone Response To Iron Ion Negative Regulation Of Epithelial Cell Differentiation Transcription, DNA-templated Response To Mineralocorticoid Chromatin Organization Regulation Of Catalytic Activity RNA Biosynthetic Process Positive Regulation Of Receptor Activity Mammary Gland Alveolus Development	Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Cell Cycle Regulation Of Cell Cycle Process Regulation Of Protein Phosphorylation Negative Regulation Of Phosphorylation Regulation Of Phosphorylation Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Arrest Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Regulation Of Cellular Localization Positive Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Response To Corticosterone Cell Cycle Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Catalytic Activity Positive Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Mineralocorticoid Positive Regulation Of Oxidoreductase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Fc Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transferase Activity Cell Cycle Arrest Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Response To Organic Cyclic Compound Detection Of Calcium Ion
Tagcloud ?			associations blotting ccnd1 dab2 dact1 day detect displayed expressions fosl1 increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt
Tagcloud (Difference) ?			associations blotting ccnd1 dab2 dact1 day detect displayed expressions fosl1 increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt
Tagcloud (Intersection) ?