NCAPD2 and ERC1

		NCAPD2	ERC1
Description		non-SMC condensin I complex subunit D2	ELKS/RAB6-interacting/CAST family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Condensed Chromosome, Centromeric Region Condensed Chromosome Condensed Nuclear Chromosome Condensin Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Membrane Centriolar Satellite Ciliary Basal Body	Golgi Membrane Podosome Cytoplasm Golgi Apparatus Centrosome Cytoskeleton Plasma Membrane IkappaB Kinase Complex Membrane Ciliary Basal Body Presynaptic Membrane Cell Projection Synapse Anchoring Junction Presynapse Presynaptic Active Zone Cytoplasmic Component
	Molecular Function	Protein Binding Histone Binding	Protein Binding PDZ Domain Binding Small GTPase Binding Cadherin Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process	Mitotic Cell Cycle Mitotic Chromosome Condensation Meiotic Chromosome Condensation Chromosome Condensation Cell Division Positive Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Separation Positive Regulation Of Chromosome Condensation	Regulation Of DNA-templated Transcription I-kappaB Phosphorylation Protein Transport Retrograde Transport, Endosome To Golgi Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body mass index ( 26426971) Femur bone mineral density x serum urate levels interaction ( 34046847) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420) Medial temporal lobe substructure volumes ( 32768867) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: CDC42 CDK1 CNN1 CSNK2A1 SMC2 SMC4 SUMO2	11 interacting genes: APP DNAJC5 DYRK1A ITSN2 PPFIA1 RAB6A RAB6B RIMS1 SRPK2 UBC YWHAG
Entrez ID		9918	23085
HPRD ID		06472	06181
Ensembl ID		ENSG00000010292	ENSG00000082805
Uniprot IDs		B3KMS0 B3KY03 Q15021	G8JLD3 Q8IUD2 X6RLX0 X6RM00
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Segregation Chromosome Condensation Positive Regulation Of Cell Cycle Process Regulation Of Chromosome Separation Condensin Complex Meiotic Chromosome Condensation Positive Regulation Of Chromosome Condensation Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Chromosome Organization Meiotic Chromosome Segregation Regulation Of Chromosome Condensation Mitotic Chromosome Condensation Kinetochore Organization Regulation Of Cell Cycle Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Organelle Organization Protein Localization To Site Of Double-strand Break Positive Regulation Of Chromosome Separation Regulation Of Chromosome Organization Positive Regulation Of Growth Organelle Organization Condensed Nuclear Chromosome Nuclear Chromosome Segregation Chromosome Organization Involved In Meiotic Cell Cycle Pronuclear Fusion Chromosome Organization Nucleotide Binding Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Cell Division DNA Damage Checkpoint Signaling GBD Domain Binding Storage Vacuole Nuclear Division Positive Regulation Of Cellular Component Organization Protein Localization To Chromosome Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Golgi Organization Regulation Of Organelle Organization Chromatin Binding Cyclin-dependent Protein Kinase Activity Supramolecular Fiber Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body	Presynapse Endosome To Plasma Membrane Transport Vesicle Protein Localization To Golgi Membrane Vesicle-mediated Transport RAGE Receptor Binding Regulation Of Neuron Apoptotic Process Astrocyte Activation Positive Regulation Of Superoxide Anion Generation Myosin V Binding Positive Regulation Of Dendrite Extension Vesicle-mediated Transport In Synapse Regulation Of Modification Of Synaptic Structure Regulation Of Modification Of Postsynaptic Structure Regulation Of Superoxide Anion Generation Positive Regulation Of Monocyte Chemotaxis Protein Localization To Golgi Apparatus Regulation Of Superoxide Metabolic Process Microglial Cell Activation Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Monocyte Chemotaxis Leukocyte Activation Involved In Inflammatory Response Synaptic Vesicle Exocytosis Intra-Golgi Vesicle-mediated Transport Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Histone H3T45 Kinase Activity Peptidyl-cysteine Methylation Protein Methylation Positive Regulation Of Vitamin D 24-hydroxylase Activity Presynaptic Active Zone Positive Chemotaxis Regulation Of Cellular Component Organization Positive Regulation Of ERK1 And ERK2 Cascade Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Modulation Of Excitatory Postsynaptic Potential
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