NCAPD2 and SMC4

Number of citations of the paper that reports this interaction (PMID 10958694)
34

Data Source:
HPRD (in vivo)

		NCAPD2	SMC4
Gene Name		non-SMC condensin I complex, subunit D2	structural maintenance of chromosomes 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Condensed Chromosome Condensin Complex Condensin Core Heterodimer Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Pronucleus	Condensin Complex Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Histone Binding	Protein Binding ATP Binding Protein Heterodimerization Activity
	Biological Process	Mitotic Cell Cycle Mitotic Chromosome Condensation Cell Division	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization
Pathways		Mitotic Prometaphase Cell Cycle, Mitotic M Phase Condensation of Prometaphase Chromosomes	Mitotic Prometaphase Mitotic Prophase Condensation of Prophase Chromosomes Cell Cycle, Mitotic M Phase Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CDK1 CSNK2A1 NCAPH SMC2 SMC4	3 interactors: NCAPD2 SMC2 TRAF3IP1
Entrez ID		9918	10051
HPRD ID		06472	09276
Ensembl ID		ENSG00000010292	ENSG00000113810
Uniprot IDs		B3KMS0 B3KY03 F5GZJ1 Q15021	E9PD53 Q9NTJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Condensation Mitotic Chromosome Condensation DNA Packaging Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Conformation Change Meiotic Chromosome Condensation Mitotic Nuclear Division Cell Cycle Process Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Cell Division Cell Cycle Chromosome Segregation Kinetochore Organization Chromosome Organization DNA Metabolic Process Meiotic Chromosome Segregation Pronuclear Fusion Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Checkpoint Meiotic Nuclear Division Nitrogen Compound Metabolic Process Meiotic Cell Cycle Reproduction Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Growth Cell Cycle Checkpoint Regulation Of Schwann Cell Differentiation Organelle Organization Protein Localization To Kinetochore Protein Localization To Chromosome, Centromeric Region Positive Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Protein Catabolic Process Axon Guidance Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Regulation Of Protein Import Into Nucleus, Translocation Mitotic G2 DNA Damage Checkpoint Ventricular Cardiac Muscle Cell Development Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Response To Copper Ion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis	Mitotic Chromosome Condensation Chromosome Condensation Mitotic Sister Chromatid Segregation Sister Chromatid Segregation DNA Packaging Chromosome Segregation DNA Conformation Change Mitotic Nuclear Division Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Cell Division Meiotic Chromosome Condensation Negative Regulation Of Interferon-beta Production Mitotic Cell Cycle Process Organelle Organization Post-anal Tail Morphogenesis Mitotic Cell Cycle Negative Regulation Of Defense Response To Virus Kinetochore Organization Negative Regulation Of Embryonic Development Negative Regulation Of Smoothened Signaling Pathway Intraciliary Transport Regulation Of Interferon-beta Production Chromosome Organization Cell Cycle Process Negative Regulation Of Type I Interferon Production DNA Metabolic Process Embryonic Camera-type Eye Development Neural Tube Patterning Embryonic Digit Morphogenesis Cell Cycle Meiotic Chromosome Segregation Regulation Of Defense Response To Virus Embryonic Heart Tube Development Regulation Of Smoothened Signaling Pathway Regulation Of Type I Interferon Production Regulation Of Embryonic Development Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport
Tagcloud ?		aberration birc5 bub1 candidates cysts datasets defining driver dysregulated epcam epithelium estrous fallopian hormones inclusion list nuak2 ovarian ovulation ovulations ovulatory prioritised proestrus publically represented segregation serous silico tube	affymetrix annotations apdf aurka bicarbonate blpdf bpdf buffered ccnb1 ccne2 cdk1 containingpdf cpdf diamond diluted genechip icodextrin insufficiently ipdf kif11 kif14 lpdf mesothelial omentum pdf pmc repressors u133plus2 uremic
Tagcloud (Difference) ?		aberration birc5 bub1 candidates cysts datasets defining driver dysregulated epcam epithelium estrous fallopian hormones inclusion list nuak2 ovarian ovulation ovulations ovulatory prioritised proestrus publically represented segregation serous silico tube	affymetrix annotations apdf aurka bicarbonate blpdf bpdf buffered ccnb1 ccne2 cdk1 containingpdf cpdf diamond diluted genechip icodextrin insufficiently ipdf kif11 kif14 lpdf mesothelial omentum pdf pmc repressors u133plus2 uremic
Tagcloud (Intersection) ?