TELO2 and KRT15

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		TELO2	KRT15
Description		telomere maintenance 2	keratin 15
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Chromosome Cytoplasm Cytosol Membrane Nuclear Body TTT Hsp90 Cochaperone Complex	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Telomeric DNA Binding Protein-containing Complex Binding Hsp90 Protein Binding Molecular Adaptor Activity	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis Scaffold Protein Binding
	Biological Process	Protein Stabilization 'de Novo' Cotranslational Protein Folding Positive Regulation Of DNA Damage Checkpoint	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 30891314)
Interacting Genes		4 interacting genes: CACNA1A KAT5 KRT15 MTOR	144 interacting genes: ABI2 ABI3 ABLIM1 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5PO BEX2 C1orf216 CALCOCO1 CARD9 CATSPERT CCDC120 CCDC185 CCDC187 CCDC87 CCHCR1 CCNB1IP1 CCNC CDK18 CEP57 COX5B CREB5 CYTH4 DEPP1 DES DEUP1 DGCR6L DRC4 DTNB EFHC1 ENKD1 EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAPLN2 HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KDM1A KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT1 KRT18 KRT19 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RAMAC RCOR3 RHPN1 RIBC1 RIBC2 RNF6 RPP25 RSPH14 SGF29 SIRPA SMARCB1 SMARCD1 SMARCE1 SNAPIN SPG21 SSX2IP TBC1D21 TCHP TEKT4 TELO2 TIMM8A TLE5 TMSB4X TRIM42 TRIML2 TSG101 TTC23 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638 ZNF688
Entrez ID		9894	3866
HPRD ID		10016	01009
Ensembl ID		ENSG00000100726	ENSG00000171346
Uniprot IDs		B4DXS2 Q9Y4R8	B3KVF5 P19012
PDB IDs		4PSI 7F4U 7OLE
Enriched GO Terms of Interacting Partners?		Cellular Response To Oxygen-containing Compound Positive Regulation Of Pentose-phosphate Shunt Positive Regulation Of Cytoplasmic Translational Initiation Response To Methionine Germ Cell Development Regulation Of Circadian Rhythm TORC1 Complex Inositol Hexakisphosphate Binding Organelle Organization RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding Regulation Of Locomotor Rhythm Regulation Of NADP Metabolic Process Positive Regulation Of Autophagy Macroautophagy TFIIIC-class Transcription Factor Complex Binding Regulation Of Pentose-phosphate Shunt Pyrimidine Nucleobase Biosynthetic Process RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding Regulation Of Organelle Assembly Regulation Of Cell Projection Assembly Negative Regulation Of TORC2 Signaling Cellular Response To Methionine Voluntary Musculoskeletal Movement Cellular Response To Nutrient Levels 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Regulation Of Macroautophagy Organelle Assembly Negative Regulation Of Lysosome Organization Cellular Response To Starvation Tissue Development Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Lipid Biosynthetic Process Positive Regulation Of T Cell Activation T-helper 1 Cell Lineage Commitment Cytoskeleton Organization RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Response To Starvation Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells Regulation Of Lipid Biosynthetic Process Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Intraciliary Transport Particle A Neural Tube Patterning Cone Photoreceptor Outer Segment Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Histone H2AK5 Acetyltransferase Activity Piccolo Histone Acetyltransferase Complex Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Histone H4K16 Acetyltransferase Activity Peptide Crotonyltransferase Activity	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Cytoskeleton Structural Constituent Of Cytoskeleton Microtubule-based Process Intermediate Filament Cytoskeleton Microtubule-based Movement Centrosome Axonemal A Tubule Inner Sheath Flagellated Sperm Motility Sperm Motility Intermediate Filament Polymerization Or Depolymerization Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Brahma Complex NpBAF Complex Establishment Of Cell Polarity Involved In Ameboidal Cell Migration RSC-type Complex Regulation Of Sister Chromatid Segregation NBAF Complex Cell Projection Microtubule Cytoskeleton Organization Motile Cilium Nucleosome Disassembly Microtubule Cilium Movement Sperm Mitochondrial Sheath Assembly Protein-DNA Complex Disassembly
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