ZEB2 and SMAD3

  • Number of citations of the paper that reports this interaction (PMID 10400677)
  • 88
  • Data Source:
  • HPRD (two hybrid)

ZEB2

SMAD3

Gene Name zinc finger E-box binding homeobox 2 SMAD family member 3
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 11 interactors: APP CBX4 COPS6 CTBP1 CTBP2 SMAD1 SMAD2 SMAD3 SMAD5 SMAD9 UBE2I 268 interactors: AATF ACTB AES AKT1 ANAPC10 ANK3 APMAP APOB APP AR ARHGEF6 ATF2 ATF3 AXIN1 AXIN2 BLZF1 BPTF BRCA1 BRCA2 BTRC C10orf54 CAMK2G CCDC33 CDC16 CDC25A CDC27 CDK2 CDK4 CDK8 CDK9 CEBPA CEBPB CEBPD CFDP1 CFH CFLAR CHRD CLASRP CORO1A CPSF7 CPTP CREBBP CSH2 CSNK1D CSNK1G2 CTCF CTNNB1 CUL1 CXXC5 CYP11A1 DAB2 DACH1 DDX5 DEDD DNAJB4 DVL1 E2F4 E2F5 EBI3 EID2 EIF4ENIF1 EP300 EPAS1 EPB41 ERBB2IP ESR1 ESR2 ETS1 FBLN1 FHL2 FHL3 FLI1 FLNA FOS FOXG1 FOXH1 FOXO1 FOXO3 FOXO4 GGA1 GIT2 GLI3 GMEB1 GSC GSK3B GTF2IRD1 HDAC1 HDAC4 HDAC5 HEY1 HEYL HGS HIPK2 HIVEP1 HMGA2 HNF4A HNRNPK HOXC11 HP HSPA4 IL37 ISL1 ITCH JPH3 JUN JUNB JUND KANSL1 KAT2B KDM2A KMT2B KPNB1 KRT10 KRT2 LBP LCK LEF1 LMNA MAGI2 MAP3K7 MAPK1 MAPK14 MAPK8 MAPK9 MAX MBD1 MCM3AP MDM4 MECOM MED15 MEN1 MEOX2 MTF2 MYC MYD88 MYO5B MYOCD MYOD1 NCOA6 NEDD4 NEDD4L NEDD9 NF1 NFYC NOTCH1 NOTCH4 NR3C1 NR4A1 NUP153 NUP214 OTUB1 PAEP PAPPA PARD3 PARD3B PARP4 PAX8 PCDH1 PCK2 PEX6 PHC2 PIAS2 PIAS3 PIAS4 PIK3CA PIN1 PLAG1 PLAGL1 PLG PML PPM1A PPP1R12C PPP2R1A PRDM4 PRKAR1B PRKAR2A PROX1 PRTN3 PSMD11 RAB38 RANBP9 RARG RASD2 RASL12 RBL1 RBX1 RCVRN RELA RIOK2 RIT1 RNF111 RNF31 RPA1 RPLP0 RRAS2 RUNX2 RUNX3 S100A4 SAP130 SERTAD1 SETD2 SF3A1 SF3B2 SIN3A SKI SKIL SKOR2 SMAD1 SMAD2 SMAD4 SMAD9 SMURF1 SMURF2 SNRNP70 SNW1 SP1 SPTBN1 SQSTM1 SREBF2 SRY SS18L1 ST6GALNAC2 STRAP STUB1 SVEP1 TANK TDP2 TEKT4 TF TFE3 TGFBR1 TGFBR2 TGIF1 TGIF2 TGM2 TLR4 TMED1 TOB1 TP53 TP73 TPM3 TSC2 TSC22D4 UBQLN4 UCHL5 USP15 USP7 VDR VIM WEE1 WWP1 WWP2 XRCC6 YBX1 YY1 ZBTB16 ZBTB3 ZC3H12A ZCCHC14 ZDHHC4 ZEB1 ZEB2 ZFYVE9 ZMYM2 ZMYND11 ZNF329 ZNF8 ZNF83
Entrez ID 9839 4088
HPRD ID 05780 04380
Ensembl ID ENSG00000169554 ENSG00000166949
Uniprot IDs O60315 P84022 Q9P0T0
PDB IDs 2DA7 1MHD 1MJS 1MK2 1OZJ 1U7F 2LAJ 2LB2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
17q12  3d  acinar  acquisition  amplicon  anoikis  coamplified  disrupted  emt  enhances  epithelial  erbb2  escape  foxc2  inducing  mammary  mcf10a  mesenchymal  overexpression  polarity  proliferative  rara  slug  steps  transformation  transition  tumorigenesis  tumorigenic  zeb1 
adenoviral  autoinhibitory  cdk  coactivators  competing  conformational  constructs  creb  define  e1a  effector  facilitating  fragment  interacting  modulates  oncoprotein  p15  p300  participate  possibility  potentiates  removes  smad4  smads  squelching  tgf  transactivation  transduce 
Tagcloud (Difference) ?
17q12  3d  acinar  acquisition  amplicon  anoikis  coamplified  disrupted  emt  enhances  epithelial  erbb2  escape  foxc2  inducing  mammary  mcf10a  mesenchymal  overexpression  polarity  proliferative  rara  slug  steps  transformation  transition  tumorigenesis  tumorigenic  zeb1 
adenoviral  autoinhibitory  cdk  coactivators  competing  conformational  constructs  creb  define  e1a  effector  facilitating  fragment  interacting  modulates  oncoprotein  p15  p300  participate  possibility  potentiates  removes  smad4  smads  squelching  tgf  transactivation  transduce 
Tagcloud (Intersection) ?