UBXN7 and FAM168A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBXN7	FAM168A
Description		UBX domain protein 7	family with sequence similarity 168 member A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol VCP-NPL4-UFD1 AAA ATPase Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Positive Regulation Of Base-excision Repair
Pathways		Neddylation KEAP1-NFE2L2 pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) IgM levels ( 28628107)	Apolipoprotein A1 levels ( 32203549) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30061609) Platelet count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Refractive error ( 32231278) Waist-hip ratio ( 28552196)
Interacting Genes		34 interacting genes: APP CLEC19A CRX CYSRT1 DAZAP2 FAM120A FAM168A FLG IGF2BP1 IGF2BP2 IGF2BP3 LARP1 MAP3K1 MEOX1 MTDH MUL1 NEDD8 NFYC PABPC4 PAX5 PAX6 REL RNF111 RPS3 RPS3A SMURF1 TRAF6 TRIM39 TRIM62 TRIM8 UBC UBQLN1 UBQLN2 ZNRF1	77 interacting genes: AKT1 ALKBH4 ATXN1 ATXN1L BOLL C10orf55 C1orf94 CALCOCO2 CAMK2A DAB1 DAZAP2 DCUN1D1 DTX2 EPN2 EPN3 FAM168B FBXW5 HGS HIP1 HR KLHL42 KRTAP19-1 KRTAP19-5 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 MEIS2 NAF1 NFYC OTUB2 OTULIN PATZ1 PEF1 PITX1 PLEKHB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PSORS1C1 R3HDM2 RBFOX1 RBPMS RBPMS2 RHOXF2 RNF216 RPS27A SECISBP2 SF1 SMAP2 SNRPC SS18L1 TAX1BP1 TFAP2D TFG TIAL1 TNIP1 TNK1 TOLLIP UBA52 UBAC1 UBASH3B UBB UBC UBE2V1 UBQLN2 UBXN6 UBXN7 VPS37C YOD1 YTHDF1
Entrez ID		26043	23201
HPRD ID		19396	13792
Ensembl ID		ENSG00000163960	ENSG00000054965
Uniprot IDs		O94888	Q92567
PDB IDs		1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Metabolic Process MRNA 5'-UTR Binding Positive Regulation Of Metabolic Process Protein Metabolic Process Regulation Of Primary Metabolic Process Cytoplasmic Stress Granule Protein Ubiquitination Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Activity Regulation Of Protein Metabolic Process Protein Modification By Small Protein Conjugation Protein Polyubiquitination CRD-mediated MRNA Stabilization N6-methyladenosine-containing RNA Reader Activity Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Base-excision Repair Macromolecule Metabolic Process Post-translational Protein Modification Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction MRNA 3'-UTR Binding Translation Regulator Activity Cytosol Regulation Of RNA Metabolic Process Regulation Of Proteolysis MRNA Stabilization Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization NF-kappaB Complex Regulation Of Base-excision Repair Positive Regulation Of Protein Metabolic Process Negative Regulation Of Translation Nucleus Regulation Of MRNA Stability Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Protein Modification Process Proteolysis Involved In Protein Catabolic Process Negative Regulation Of MRNA Metabolic Process Cytoplasm Regulation Of RNA Stability Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process	Protein Tag Activity Intermediate Filament Post-translational Protein Modification Ubiquitin Protein Ligase Binding Protein Binding Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Ubiquitination Cytoplasmic Stress Granule Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Positive Regulation Of Post-translational Protein Modification Macromolecule Catabolic Process Autophagy Proteolysis Regulation Of Post-translational Protein Modification POZ Domain Binding Cytosol Positive Regulation Of Protein Monoubiquitination Identical Protein Binding Protein Modification Process Regulation Of Protein Monoubiquitination Glutamate Receptor Binding Clathrin-coated Vesicle Ubiquitin Conjugating Enzyme Binding RNA Stabilization Clathrin Binding Clathrin Vesicle Coat Regulation Of MRNA Metabolic Process Protein Metabolic Process Catabolic Process Endosome Transport Via Multivesicular Body Sorting Pathway Macroautophagy Negative Regulation Of RNA Catabolic Process Cytoplasm Positive Regulation Of Macromolecule Metabolic Process MRNA Binding Protein K11-linked Deubiquitination RNA Binding Vesicle Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Translational Initiation Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Multivesicular Body Sorting Pathway Ubiquitin Binding Proteasomal Protein Catabolic Process
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