UBXN7 and FAM120A

Number of citations of the paper that reports this interaction (PubMedID 37744330)
51

Data Source:
BioGRID (unspecified method)

		UBXN7	FAM120A
Description		UBX domain protein 7	family with sequence similarity 120 member A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol VCP-NPL4-UFD1 AAA ATPase Complex	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Binding Protein Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Neddylation KEAP1-NFE2L2 pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) IgM levels ( 28628107)	Ability to confide in someone ( 29970889) Anxiety ( 33859377) Body mass index ( 25953783) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Coffee consumption ( 31046077) Depression ( 33859377) Intelligence (MTAG) ( 29326435) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Multisite chronic pain ( 33830993) Upper eyelid morphology ( 29921221)
Interacting Genes		34 interacting genes: APP CLEC19A CRX CYSRT1 DAZAP2 FAM120A FAM168A FLG IGF2BP1 IGF2BP2 IGF2BP3 LARP1 MAP3K1 MEOX1 MTDH MUL1 NEDD8 NFYC PABPC4 PAX5 PAX6 REL RNF111 RPS3 RPS3A SMURF1 TRAF6 TRIM39 TRIM62 TRIM8 UBC UBQLN1 UBQLN2 ZNRF1	10 interacting genes: ATP5F1C CEBPA DYSF LCOR NEIL3 PRKN RBPMS RNF10 SNCA UBXN7
Entrez ID		26043	23196
HPRD ID		19396	12928
Ensembl ID		ENSG00000163960	ENSG00000048828
Uniprot IDs		O94888	A0A8V8TNY3 Q9NZB2
PDB IDs		1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Metabolic Process MRNA 5'-UTR Binding Positive Regulation Of Metabolic Process Protein Metabolic Process Regulation Of Primary Metabolic Process Cytoplasmic Stress Granule Protein Ubiquitination Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Activity Regulation Of Protein Metabolic Process Protein Modification By Small Protein Conjugation Protein Polyubiquitination CRD-mediated MRNA Stabilization N6-methyladenosine-containing RNA Reader Activity Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Base-excision Repair Macromolecule Metabolic Process Post-translational Protein Modification Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction MRNA 3'-UTR Binding Translation Regulator Activity Cytosol Regulation Of RNA Metabolic Process Regulation Of Proteolysis MRNA Stabilization Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization NF-kappaB Complex Regulation Of Base-excision Repair Positive Regulation Of Protein Metabolic Process Negative Regulation Of Translation Nucleus Regulation Of MRNA Stability Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Protein Modification Process Proteolysis Involved In Protein Catabolic Process Negative Regulation Of MRNA Metabolic Process Cytoplasm Regulation Of RNA Stability Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process	Dopamine Uptake Involved In Synaptic Transmission Regulation Of Neurotransmitter Secretion Catecholamine Uptake Dopamine Uptake Histone Deacetylase Binding Dopamine Transport Neurotransmitter Reuptake Synaptic Vesicle Membrane Phospholipase Binding Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Metabolic Process Synaptic Transmission, Dopaminergic Ubiquitin-specific Protease Binding Regulation Of Dopamine Secretion Cellular Response To Metal Ion Monoamine Transport Amyloid Fibril Formation Neurotransmitter Uptake Regulation Of Synaptic Vesicle Recycling Dopamine Metabolic Process Negative Regulation Of Exocytosis Terminal Bouton Regulation Of Catecholamine Secretion Regulation Of Reactive Oxygen Species Biosynthetic Process Catecholamine Metabolic Process Hsp70 Protein Binding Mitochondrion Organization Transcription Cis-regulatory Region Binding Response To Xenobiotic Stimulus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Macrophage Activation Protein Monoubiquitination Negative Regulation Of Spontaneous Neurotransmitter Secretion Protein Destabilization Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Monocyte Activation Involved In Immune Response MCM Complex Binding Macrophage Activation Regulation Of Endocytosis Generation Of Precursor Metabolites And Energy Biogenic Amine Metabolic Process Protein Autoubiquitination Response To Lipid Response To Metal Ion Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process
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