APBA2 and NECAB3

Number of citations of the paper that reports this interaction (PMID 10833507)
7

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		APBA2	NECAB3
Gene Name		amyloid beta (A4) precursor protein-binding, family A, member 2	N-terminal EF-hand calcium binding protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane	Golgi Cis Cisterna Nucleus Cytoplasm Endoplasmic Reticulum Membrane
	Molecular Function	Beta-amyloid Binding Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	In Utero Embryonic Development Synaptic Transmission Nervous System Development Locomotory Behavior Regulation Of Gene Expression Protein Transport Multicellular Organism Growth	Protein Secretion Protein Metabolic Process Regulation Of Amyloid Precursor Protein Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Temperament ( 22832960)
Protein-Protein Interactions		11 interactors: APP CLSTN1 CLSTN3 LRP1 LRP2 LRP8 MAPK6 NECAB3 NRXN1 RELA STXBP1	3 interactors: APBA2 APP IKBKG
Entrez ID		321	63941
HPRD ID		04090	07168
Ensembl ID		ENSG00000034053	ENSG00000125967
Uniprot IDs		Q59G28 Q99767	Q96P71
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Light Stimulus Response To Radiation Response To Abiotic Stimulus Synapse Assembly Phototransduction, Visible Light Retinoid Metabolic Process Endocytosis Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Detection Of Light Stimulus Nervous System Development Isoprenoid Metabolic Process Synapse Organization Secretion By Cell Detection Of Abiotic Stimulus Response To External Stimulus Signaling System Development Cell Communication Cell Adhesion Secretion Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Steroid Metabolic Process Multicellular Organismal Development Vesicle-mediated Transport Anatomical Structure Development Brain Development Anatomical Structure Morphogenesis Regulation Of Synaptic Transmission Head Development Regulation Of Protein Tyrosine Kinase Activity Generation Of Neurons Alcohol Metabolic Process Platelet Degranulation Ammon Gyrus Development Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Beta-amyloid Clearance Acetaldehyde Metabolic Process Receptor-mediated Endocytosis Neurogenesis Neuromuscular Process Controlling Balance Developmental Process Central Nervous System Development Regulation Of Synapse Structure Or Activity Blood Coagulation Hemostasis	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Locomotory Behavior Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Growth Behavior Cellular Copper Ion Homeostasis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Regulation Of Protein Kinase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Kinase Activity Activation Of NF-kappaB-inducing Kinase Activity Innate Immune Response Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of NIK/NF-kappaB Signaling Mating Behavior B Cell Homeostasis Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition NIK/NF-kappaB Signaling Apoptotic Process Regulation Of NIK/NF-kappaB Signaling Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Axon Cargo Transport Mating Neuromuscular Junction Development Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Phase Transition I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?		a4 ageing apoe4 apolipoprotein broadly carrier carriers deposition determinants encode endocytosis epsilon4 fyn implicate influenced initially load mediators modify modulators physiology pursue referred resembled rnf219 sv2a transcriptome transcriptomic unaffected
Tagcloud (Difference) ?		a4 ageing apoe4 apolipoprotein broadly carrier carriers deposition determinants encode endocytosis epsilon4 fyn implicate influenced initially load mediators modify modulators physiology pursue referred resembled rnf219 sv2a transcriptome transcriptomic unaffected
Tagcloud (Intersection) ?