APBA2

Name	amyloid beta precursor protein binding family A member 2
Structure	No pdb structure
Interactors	16 interactors: APP ARF3 ARF4 CLSTN1 CLSTN3 HUNK LRP1 LRP2 LRP8 MAGEB6 MAPK6 NECAB3 NRXN1 RELA STXBP1 USP20
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Dendritic Spine Schaffer Collateral - CA1 Synapse Presynapse
	Molecular Function	Amyloid-beta Binding Protein Binding Identical Protein Binding
	Biological Process	In Utero Embryonic Development Chemical Synaptic Transmission Nervous System Development Locomotory Behavior Regulation Of Gene Expression Protein Transport Multicellular Organism Growth Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways	Neurexins and neuroligins
GWAS	Longevity (100 years and older) ( 33948810 ) Response to mTOR inhibitor (rapamycin) ( 24009623 ) SAPHO syndrome ( 33816493 ) Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583 ) Temperament ( 22832960 )
Entrez ID	321
HPRD ID	04090
Ensembl ID	ENSG00000034053
Uniprot IDs	Q59G28 Q99767
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Synapse Organization Positive Regulation Of Synaptic Transmission Vesicle-mediated Transport Positive Regulation Of Nervous System Development Glutamatergic Synapse Low-density Lipoprotein Particle Receptor Activity Apolipoprotein Binding Establishment Of Protein Localization Calcium Ion Binding Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Cargo Receptor Activity Regulation Of Nervous System Development Protein Transport Modulation Of Chemical Synaptic Transmission Astrocyte Activation Involved In Immune Response Chemical Synaptic Transmission Intracellular Protein Localization Positive Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Developmental Process Golgi Apparatus Trans-synaptic Signaling NMDA Selective Glutamate Receptor Signaling Pathway Synaptic Signaling Regulation Of Synapse Assembly Positive Regulation Of Protein Catabolic Process In The Vacuole Positive Regulation Of Synapse Assembly Receptor Complex Clathrin-coated Pit Endocytosis Retinoid Metabolic Process Regulation Of Lysosomal Protein Catabolic Process Diterpenoid Metabolic Process Positive Regulation Of Multicellular Organismal Process Acetylcholine Receptor Binding Amyloid-beta Binding Terpenoid Metabolic Process Regulation Of Cell Junction Assembly Neuron Projection Morphogenesis Cell Projection Morphogenesis Cellular Response To Growth Factor Stimulus Isoprenoid Metabolic Process Positive Regulation Of Catabolic Process Heparan Sulfate Proteoglycan Binding Astrocyte Activation Positive Regulation Of Cell Junction Assembly Platelet Alpha Granule Transcytosis Regulation Of Amyloid-beta Clearance Cell-cell Signaling