APBA2 and CLSTN1

Number of citations of the paper that reports this interaction (PMID 12972431)
38

Data Source:
HPRD (in vivo, two hybrid)

		APBA2	CLSTN1
Gene Name		amyloid beta (A4) precursor protein-binding, family A, member 2	calsyntenin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane	Golgi Membrane Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Junction Cell Projection Postsynaptic Membrane Extracellular Vesicular Exosome
	Molecular Function	Beta-amyloid Binding Protein Binding	Beta-amyloid Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding
	Biological Process	In Utero Embryonic Development Synaptic Transmission Nervous System Development Locomotory Behavior Regulation Of Gene Expression Protein Transport Multicellular Organism Growth	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pathways
Drugs
Diseases
GWAS		Temperament ( 22832960)
Protein-Protein Interactions		11 interactors: APP CLSTN1 CLSTN3 LRP1 LRP2 LRP8 MAPK6 NECAB3 NRXN1 RELA STXBP1	14 interactors: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12
Entrez ID		321	22883
HPRD ID		04090	10837
Ensembl ID		ENSG00000034053	ENSG00000171603
Uniprot IDs		Q59G28 Q99767	B3KMD3 B4E3Q1 O94985
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Light Stimulus Response To Radiation Response To Abiotic Stimulus Synapse Assembly Phototransduction, Visible Light Retinoid Metabolic Process Endocytosis Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Detection Of Light Stimulus Nervous System Development Isoprenoid Metabolic Process Synapse Organization Secretion By Cell Detection Of Abiotic Stimulus Response To External Stimulus Signaling System Development Cell Communication Cell Adhesion Secretion Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Steroid Metabolic Process Multicellular Organismal Development Vesicle-mediated Transport Anatomical Structure Development Brain Development Anatomical Structure Morphogenesis Regulation Of Synaptic Transmission Head Development Regulation Of Protein Tyrosine Kinase Activity Generation Of Neurons Alcohol Metabolic Process Platelet Degranulation Ammon Gyrus Development Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Beta-amyloid Clearance Acetaldehyde Metabolic Process Receptor-mediated Endocytosis Neurogenesis Neuromuscular Process Controlling Balance Developmental Process Central Nervous System Development Regulation Of Synapse Structure Or Activity Blood Coagulation Hemostasis	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Response To DNA Damage Stimulus Response To Stress Antigen Processing And Presentation Of Peptide Antigen Axon Cargo Transport Peptidyl-lysine Modification Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Antigen Processing And Presentation Regulation Of DNA Repair Cellular Response To UV-C Cellular Response To Vitamin B1 Negative Regulation Of Thymidylate Synthase Biosynthetic Process Microtubule-based Movement Movement Of Cell Or Subcellular Component Cellular Response To DNA Damage Stimulus Stress Granule Disassembly Negative Regulation Of Protein Metabolic Process Blood Coagulation Negative Regulation Of Histone H2A K63-linked Ubiquitination Hemostasis Negative Regulation Of Cell Cycle Response To Radiation Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Traversing Start Control Point Of Mitotic Cell Cycle Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cell Cycle Process Microtubule-based Transport DNA Metabolic Process Cytoskeleton-dependent Intracellular Transport Response To Vitamin B1 Response To Ether Cell Cycle Arrest Cellular Component Assembly Cellular Response To Copper Ion Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair Negative Regulation Of Calcium-mediated Signaling Regulation Of Body Fluid Levels Behavior Protein Localization To Nucleus Negative Regulation Of DNA Repair DNA Repair Chromatin Modification Wound Healing Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-17 Production Histone H3-K9 Trimethylation
Tagcloud ?		a4 ageing apoe4 apolipoprotein broadly carrier carriers deposition determinants encode endocytosis epsilon4 fyn implicate influenced initially load mediators modify modulators physiology pursue referred resembled rnf219 sv2a transcriptome transcriptomic unaffected	adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Difference) ?		a4 ageing apoe4 apolipoprotein broadly carrier carriers deposition determinants encode endocytosis epsilon4 fyn implicate influenced initially load mediators modify modulators physiology pursue referred resembled rnf219 sv2a transcriptome transcriptomic unaffected	adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Intersection) ?