IFFO1 and TCHP

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		IFFO1	TCHP
Description		intermediate filament family orphan 1	trichoplein keratin filament binding
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nucleoplasm Intermediate Filament Membrane Nuclear Matrix Site Of Double-strand Break	Cytoplasm Mitochondrion Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Membrane Desmosome Nuclear Membrane Ciliary Basal Body Keratin Filament Apical Cortex Anchoring Junction Polymeric Cytoskeletal Fiber
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Protein Localization To Site Of Double-strand Break DNA Double-strand Break Attachment To Nuclear Envelope	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 28552196)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Myocardial infarction ( 30226566) Platelet count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		8 interacting genes: ACAP1 GFI1B LMNA NDN RHOU RNF183 TCHP XRCC4	52 interacting genes: ATPAF2 BCAS2 C21orf91 CBY2 CCDC125 CCDC13 CCDC172 CCDC85B CDR2 CDR2L DMAP1 DYDC1 EIF4ENIF1 HOOK2 ID2 IFFO1 IKZF3 KCTD17 KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT32 KRT34 KRT35 KRT40 KRT5 KRT6A KRT75 KRT8 MIIP MIPOL1 MKRN3 MTUS2 NAB2 NDOR1 NME7 NUP54 PRDM16 PSMB5 RABGEF1 RUSC1 TEX11 TRIM27 TRIM54 USHBP1 VIM WWOX ZIM2
Entrez ID		25900	84260
HPRD ID		09988	14403
Ensembl ID		ENSG00000010295	ENSG00000139437
Uniprot IDs		A0A087WZ16 B4DQQ1 Q0D2I5 Q6P593	Q9BT92
PDB IDs		6ABO
Enriched GO Terms of Interacting Partners?			Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Structural Molecule Activity Cytoskeleton Organization Cytoskeleton Structural Constituent Of Cytoskeleton Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Cell Differentiation Cellular Developmental Process Organelle Organization Protein Binding Scaffold Protein Binding Epidermis Development Cytosol Keratinization Keratin Filament Binding Cell Periphery Developmental Process Anatomical Structure Morphogenesis Intermediate Filament Cytoskeleton Nuclear Matrix Cornified Envelope Hair Cycle Centrosome Hepatocyte Apoptotic Process
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