HAPLN2 and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HAPLN2	TFCP2
Description		hyaluronan and proteoglycan link protein 2	transcription factor CP2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Node Of Ranvier Synapse Perineuronal Net	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Hyaluronic Acid Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Skeletal System Development Cell Adhesion Central Nervous System Development Establishment Of Blood-nerve Barrier Extracellular Matrix Assembly	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Interacting Genes		47 interacting genes: ASB13 BANP CCDC125 CIDEB EXOSC8 FHL3 FHL5 FNDC3B GOLGA6L9 GPRIN2 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT40 KRT85 KRTAP10-8 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP6-2 KRTAP6-3 KRTAP9-2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OIP5 PFDN5 PM20D2 PNMA1 PNMA2 PPP1R16B PSTPIP1 SEC13 SSC4D TFCP2 TRIM23 TRIM27 VWC2 ZMYND12 ZNF438 ZNF655	73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		60484	7024
HPRD ID		17088	01790
Ensembl ID		ENSG00000132702	ENSG00000135457
Uniprot IDs		B7Z1R1 Q9GZV7	Q12800
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Identical Protein Binding Cytoskeleton Organization Epidermis Development Keratinization Negative Regulation Of Viral Transcription COPII Vesicle Coat Suppression Of Viral Release By Host Protein Binding COPII-coated Vesicle Cargo Loading Regulation Of Viral Transcription Cytosol Cytoskeleton	Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic
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