CD72 and CD5

Number of citations of the paper that reports this interaction (PMID 1711157)
43

Data Source:
HPRD (in vitro, in vivo)

		CD72	CD5
Gene Name		CD72 molecule	CD5 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Receptor Binding Protein Binding Carbohydrate Binding	Receptor Activity Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding
	Biological Process	Cell Adhesion Signal Transduction Axon Guidance	Receptor-mediated Endocytosis Cell Recognition Cell Proliferation T Cell Costimulation Apoptotic Signaling Pathway
Pathways		Axon guidance Semaphorin interactions Other semaphorin interactions
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088)
Protein-Protein Interactions		7 interactors: BLNK CD5 GRB2 LYN PTPN6 SEMA4D SYK	22 interactors: CAMK2D CBL CD2 CD247 CD27 CD4 CD6 CD72 CD79A CD79B CSNK2A1 DYNLT3 FYN HNRNPU LCK PIK3R1 PRKCA PRKCB PRKCG PTPN6 RASA1 ZAP70
Entrez ID		971	921
HPRD ID		00118	01078
Ensembl ID		ENSG00000137101	ENSG00000110448
Uniprot IDs		P21854 Q5TLG3	P06127
PDB IDs			2JA4 2JOP 2JP0 2OTT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Positive Regulation Of Cell-cell Adhesion T Cell Costimulation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Immune System Process Regulation Of Cell Activation B Cell Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Platelet Activation Positive Regulation Of Signal Transduction Immune Response Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Amino Acid Metabolic Process Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Regulation Of Cellular Ketone Metabolic Process Antigen Receptor-mediated Signaling Pathway Regulation Of B Cell Receptor Signaling Pathway Locomotion Regulation Of Platelet Aggregation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Immune System Process Regulation Of Phosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Defense Response Regulation Of Body Fluid Levels Wound Healing Chemotaxis Regulation Of MAPK Cascade Hemopoiesis Regulation Of Signal Transduction Positive Regulation Of Immune Response Regulation Of ERK1 And ERK2 Cascade	Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Cell Activation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Immune System Process Regulation Of Lymphocyte Activation Regulation Of Cell Adhesion T Cell Costimulation Positive Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Signal Transduction B Cell Receptor Signaling Pathway Immune Response Signal Transduction Platelet Activation Positive Regulation Of T Cell Activation T Cell Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Adhesion Innate Immune Response Signaling Leukocyte Migration Cell Communication Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Regulation Of Immune Response Blood Coagulation Hemostasis Locomotion Leukocyte Activation Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Defense Response To Virus By Virus Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Cellular Response To Stimulus Response To Fibroblast Growth Factor Movement Of Cell Or Subcellular Component Protein Autophosphorylation Regulation Of Body Fluid Levels
Tagcloud ?		ag b bcr blk blocked btk cyclosporin events fk506 gamma2 glycoprotein igm immunosuppressive initiating ligated ligation lyn mature mobilization phospholipase spite stimulated substitute surprisingly syk tec tyrosine unresponsive xid	bmt cd11b cd11c cd19 cd45 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained
Tagcloud (Difference) ?		ag b bcr blk blocked btk cyclosporin events fk506 gamma2 glycoprotein igm immunosuppressive initiating ligated ligation lyn mature mobilization phospholipase spite stimulated substitute surprisingly syk tec tyrosine unresponsive xid	bmt cd11b cd11c cd19 cd45 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained
Tagcloud (Intersection) ?