CD72 and MS4A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD72	MS4A7
Description		CD72 molecule	membrane spanning 4-domains A7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Trans-Golgi Network Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Carbohydrate Binding	Protein Binding
	Biological Process	Cell Adhesion Negative Regulation Of B Cell Receptor Signaling Pathway	Cell Surface Receptor Signaling Pathway
Pathways		Other semaphorin interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Electroencephalogram traits ( 25387704)	Iron status biomarkers (ferritin levels) ( 33536631) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494)
Interacting Genes		22 interacting genes: ATP6AP2 BIK BLNK CD5 CGRRF1 CLDN7 CREB3L1 GPR152 GRAMD1C GRB2 LHFPL5 LMNA LRRC25 LSMEM2 LYN MS4A3 MS4A7 NRG1 PTPN6 SEMA4D SPACA1 SYK	10 interacting genes: CD72 DRAM1 EMP1 HMGCL IGFBP5 ITGB2 LAT PLN PMP22 SLC35F6
Entrez ID		971	58475
HPRD ID		00118	07579
Ensembl ID		ENSG00000137101	ENSG00000166927
Uniprot IDs		P21854 Q5TLG3	Q9GZW8
PDB IDs
Enriched GO Terms of Interacting Partners?		B Cell Receptor Signaling Pathway T Cell Costimulation Membrane Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell Adhesion Phosphotyrosine Residue Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin SH2 Domain Binding Peptidyl-tyrosine Phosphorylation Regulation Of Cell Adhesion Plasma Membrane Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Immune Response-activating Signaling Pathway Phosphorylation-dependent Protein Binding Negative Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cell Activation Regulation Of T Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Neutrophil Activation Involved In Immune Response Regulation Of MAPK Cascade Negative Regulation Of Immune Response Immune Response-regulating Signaling Pathway Activation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Lymphocyte Activation Regulation Of Mast Cell Activation Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin Phospholipase Binding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Cellular Component Biogenesis Regulation Of Lymphocyte Activation Regulation Of Cell-cell Adhesion SH3 Domain Binding Negative Regulation Of Defense Response Regulation Of ERK1 And ERK2 Cascade Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of B Cell Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Chemorepellent Activity Ephrin Receptor Binding Neutrophil Activation	Bleb Assembly Apoptotic Process Hydroxymethylglutaryl-CoA Lyase Activity Oxo-acid-lyase Activity Negative Regulation Of Skeletal Muscle Hypertrophy Integrin AlphaM-beta2 Complex Integrin AlphaX-beta2 Complex Integrin AlphaL-beta2 Complex Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process TCR Signalosome Cell Death Programmed Cell Death Insulin-like Growth Factor Binding Protein Complex ICAM-3 Receptor Activity Positive Regulation Of Neutrophil Degranulation Integrin-mediated Signaling Pathway Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?