CD53 and CD9

Number of citations of the paper that reports this interaction (PMID 11959120)
33

Data Source:
HPRD (in vitro)

		CD53	CD9
Gene Name		CD53 molecule	CD9 molecule
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Plasma Membrane Cell-cell Junction Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Integrin Binding Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Myoblast Fusion	Platelet Degranulation Movement Of Cell Or Subcellular Component Cell Adhesion Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Brain Development Blood Coagulation Negative Regulation Of Cell Proliferation Pathogenesis Response To Water Deprivation Oligodendrocyte Development Platelet Activation Paranodal Junction Assembly Multicellular Organism Reproduction
Pathways			Uptake and actions of bacterial toxins Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Fertilization Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs
Diseases
GWAS		Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)	Mean platelet volume ( 22139419) Paclitaxel-induced neuropathy ( 23776197) Platelet counts ( 22139419)
Protein-Protein Interactions		6 interactors: CD2 CD4 CD9 GGT1 IL2 IL4	22 interactors: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT PRKCA PTGFRN SERPINH1 TSPAN4 VKORC1
Entrez ID		963	928
HPRD ID		01054	00880
Ensembl ID		ENSG00000143119	ENSG00000010278
Uniprot IDs		B4DQB5 P19397	B4DK09 P21926
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Activation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Positive Regulation Of Cytokine Production Regulation Of Cell-cell Adhesion Positive Regulation Of Isotype Switching To IgG Isotypes Regulation Of Lymphocyte Activation Lymphocyte Activation Regulation Of Isotype Switching To IgG Isotypes Cell Adhesion Regulation Of Cell Activation Leukocyte Activation Regulation Of T Cell Differentiation Regulation Of Immune System Process Single Organismal Cell-cell Adhesion Regulation Of Cytokine Production Positive Regulation Of Peptidyl-tyrosine Phosphorylation T Cell Differentiation Regulation Of Lymphocyte Differentiation Regulation Of Cell Adhesion Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Positive Regulation Of T Cell Activation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Activated T Cell Proliferation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Isotype Switching Lymphocyte Differentiation Positive Regulation Of Cell-cell Adhesion Regulation Of Isotype Switching Positive Regulation Of Immune System Process Regulation Of Inflammatory Response Positive Regulation Of Immunoglobulin Mediated Immune Response Regulation Of Activated T Cell Proliferation Positive Regulation Of Immunoglobulin Production Positive Regulation Of B Cell Proliferation T Cell Selection Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Interferon-gamma Production Positive Regulation Of Cell Adhesion Regulation Of B Cell Proliferation Regulation Of Cellular Amino Acid Metabolic Process Natural Killer Cell Activation	Wound Healing Blood Coagulation Hemostasis Response To Wounding Regulation Of Body Fluid Levels Response To Stress Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Adhesion Integrin-mediated Signaling Pathway Regulation Of Immune System Process Regulation Of Protein Metabolic Process Learning Or Memory Cognition Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Proliferation Cell Migration Cell Adhesion Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Regulation Of Cell Migration Extracellular Matrix Organization Associative Learning Extracellular Structure Organization Locomotion Cell Motility Positive Regulation Of Signal Transduction Regulation Of Cell Adhesion Positive Regulation Of Epithelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Tissue Development Cell-substrate Adhesion Positive Regulation Of Endocytosis Leukocyte Migration Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Single-organism Behavior Mesodermal Cell Differentiation Movement Of Cell Or Subcellular Component Positive Regulation Of Cell-substrate Adhesion Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling
Tagcloud ?		bioinformatics coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto laptm5 mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification	accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Difference) ?		bioinformatics coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto laptm5 mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification	accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Intersection) ?