CD53 and CD37

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD53	CD37
Description		CD53 molecule	CD37 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Cell-cell Junction Membrane Specific Granule Membrane Synapse Extracellular Exosome Anchoring Junction Tertiary Granule Membrane	Immunological Synapse Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Protein-membrane Adaptor Activity	Protein Binding
	Biological Process	Signal Transduction Receptor Clustering T Cell Receptor Signaling Pathway Positive Regulation Of Myoblast Fusion	Positive Regulation Of Immunoglobulin Production Regulation Of Humoral Immune Response Negative Regulation Of Myeloid Dendritic Cell Activation T Cell Proliferation Negative Regulation Of T Cell Proliferation Defense Response To Protozoan Regulation Of Defense Response To Virus
Pathways		Neutrophil degranulation
Drugs			Otlertuzumab
Diseases
GWAS		Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)
Interacting Genes		80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1	6 interacting genes: AGTR1 CD53 EMP1 GJB1 LHFPL5 LRRC3B
Entrez ID		963	951
HPRD ID		01054	01053
Ensembl ID		ENSG00000143119	ENSG00000104894
Uniprot IDs		B4DQB5 P19397	P11049
PDB IDs		6WVG
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Membrane Raft Distribution Membrane Raft Localization Protein Binding Bleb Assembly Membrane Raft Polarization T Cell Activation Endomembrane System Membrane Raft Organization Endoplasmic Reticulum Membrane Defense Response To Protozoan Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity	Angiotensin Type I Receptor Activity Plasma Membrane Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Renin-angiotensin Regulation Of Aldosterone Production Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Renal Sodium Excretion Membrane Bleb Assembly Gap Junction Assembly Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Stereocilium Bundle
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