CD53 and VSTM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD53	VSTM1
Description		CD53 molecule	V-set and transmembrane domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Cell-cell Junction Membrane Specific Granule Membrane Synapse Extracellular Exosome Anchoring Junction Tertiary Granule Membrane	Extracellular Region Extracellular Space Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein-membrane Adaptor Activity	Cytokine Activity Protein Binding
	Biological Process	Signal Transduction Receptor Clustering T Cell Receptor Signaling Pathway Positive Regulation Of Myoblast Fusion	Immune System Process Immune Response-regulating Signaling Pathway
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)	Small cell lung carcinoma ( 28604730)
Interacting Genes		80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1	29 interacting genes: ADGRG3 APH1B AQP6 ARL13B CD53 CLDN7 CLDN9 CLEC10A COQ9 ERGIC3 FAM209A FATE1 FBXO2 FCGR1A FNDC9 GJB5 GOLM1 GPX8 HCST KCNJ6 LAMP1 LMNA LRRC4C MANSC1 MRM1 PLPP2 SLC60A2 STMN4 TMEM248
Entrez ID		963	284415
HPRD ID		01054	15615
Ensembl ID		ENSG00000143119	ENSG00000189068
Uniprot IDs		B4DQB5 P19397	D2DJS5 D2DJS6 Q6UX27
PDB IDs		6WVG
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Membrane Raft Distribution Membrane Raft Localization Protein Binding Bleb Assembly Membrane Raft Polarization T Cell Activation Endomembrane System Membrane Raft Organization Endoplasmic Reticulum Membrane Defense Response To Protozoan Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity	Membrane
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