CARTPT and CEACAM6

Number of citations: 0 (PubMedID 21982860)
Data Source: BioGRID (pull down)

		CARTPT	CEACAM6
Name		CART prepropeptide	CEA cell adhesion molecule 6
Structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Synapse	Extracellular Space Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Azurophil Granule Membrane Side Of Membrane
	Molecular Function	Molecular_function Neuropeptide Hormone Activity Protein Binding	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Intracellular Glucose Homeostasis Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Adult Feeding Behavior Cellular Response To Starvation Positive Regulation Of Cell Communication Negative Regulation Of Appetite Positive Regulation Of Epinephrine Secretion Circadian Regulation Of Gene Expression Response To Morphine Positive Regulation Of MAPK Cascade Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Bone Resorption Regulation Of Bone Remodeling Regulation Of Insulin Secretion Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Biological Quality Negative Regulation Of Glucagon Secretion Somatostatin Secretion	Apoptotic Process Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis
Pathways		None	Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs		Amphetamine	None
GWAS		No GWAS studies recorded	Serum carcinoembryonic antigen levels ( 31666285 )
Interacting Genes		4 interacting genes: CEACAM1 CEACAM6 MEIS2 SDHB	32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76
Entrez ID		9607	4680
HPRD ID		04006	01233
Ensembl ID		ENSG00000164326	ENSG00000086548
Uniprot IDs		Q16568	P40199
PDB IDs		1HY9	4WHC 4WTZ 4Y8A 4YIQ
GO Terms Enriched among Interactors		Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Insulin Receptor Internalization Negative Regulation Of Cytotoxic T Cell Degranulation Negative Regulation Of Hepatocyte Proliferation Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Cardiac Muscle Myoblast Proliferation Succinate Dehydrogenase (quinone) Activity 3 Iron, 4 Sulfur Cluster Binding Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Granulocyte Colony-stimulating Factor Signaling Pathway Insulin Catabolic Process Regulation Of Homophilic Cell Adhesion Mitochondrial Electron Transport, Succinate To Ubiquinone Respiratory Chain Complex II (succinate Dehydrogenase) Ubiquinone Binding Regulation Of Myeloid Cell Differentiation Common Myeloid Progenitor Cell Proliferation Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Succinate Metabolic Process Bile Acid Transmembrane Transporter Activity Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Granulocyte Differentiation Regulation Of Blood Vessel Remodeling Negative Regulation Of Platelet Aggregation	Response To Nerve Growth Factor Cellular Response To Nerve Growth Factor Stimulus Central Nervous System Development Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Developmental Process