CEACAM6 and ZNF76

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CEACAM6	ZNF76
Description		CEA cell adhesion molecule 6	zinc finger protein 76
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Azurophil Granule Membrane Side Of Membrane	Nucleus
	Molecular Function	Protein Binding Identical Protein Binding Protein Heterodimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Apoptotic Process Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis	Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Serum carcinoembryonic antigen levels ( 31666285)	Height ( 18391951 25282103 31562340) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76	93 interacting genes: ACAT2 ALOXE3 ANKRD37 ANTKMT ATP5PO BLZF1 BOLA2 BOLA2B C10orf55 C22orf15 C3orf36 CCDC33 CEACAM6 CEP76 CSN3 DDIT4L DISC1 ENKD1 EP300 EXOSC1 FAM228A FAM90A1 FCRL4 FNDC8 FSD2 GIMAP6 GRAPL HDAC1 HOMEZ HUNK IKZF3 KCTD9 KLF15 KPNA3 KRT40 KRT75 L3MBTL3 LAP3 LETM1 LHX3 LHX4 LHX6 LIN37 LIN54 LMO1 MAGEA6 MBD3L1 MBD5 MED19 MFAP1 MORN3 MRPL12 MTFR1L MTUS2 MYL10 NEDD9 NRIP2 PIAS1 PMPCA POGZ PRKAR1B RAB3IP RALY REL RNF214 RPRD1A RPS21 SCNM1 SLAIN1 SMAD1 SNAI2 SPANXN3 SPATA8 SPMIP10 STMN3 TASOR2 TBC1D22B TBP TEKT5 TGS1 TNNI1 USP54 USP6 USP7 VXN WDR83 YPEL3 ZC2HC1C ZC4H2 ZMYM6 ZNF420 ZNF526 ZNF623
Entrez ID		4680	7629
HPRD ID		01233	01929
Ensembl ID		ENSG00000086548	ENSG00000065029
Uniprot IDs		P40199	P36508
PDB IDs		4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?		Response To Nerve Growth Factor Cellular Response To Nerve Growth Factor Stimulus Central Nervous System Development Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Developmental Process	Protein Binding Medial Motor Column Neuron Differentiation
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