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CEACAM6 and CIB1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
CEACAM6
CIB1
Description
CEA cell adhesion molecule 6
calcium and integrin binding 1
Image
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Cell Surface
Membrane
Apical Plasma Membrane
Azurophil Granule Membrane
Side Of Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Golgi Apparatus
Centrosome
Cytoskeleton
Plasma Membrane
Membrane
Apical Plasma Membrane
Nuclear Body
Lamellipodium
Axon
Growth Cone
Vesicle
Filopodium Tip
Ruffle Membrane
Sarcolemma
Cell Projection
Neuron Projection
Neuronal Cell Body
Perikaryon
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell Periphery
Molecular Function
Protein Binding
Identical Protein Binding
Protein Heterodimerization Activity
Magnesium Ion Binding
Calcium Ion Binding
Protein Binding
Calcium-dependent Protein Kinase Inhibitor Activity
Protein Serine/threonine Kinase Inhibitor Activity
Small GTPase Binding
Protein-membrane Adaptor Activity
Transmembrane Transporter Binding
Metal Ion Binding
Biological Process
Apoptotic Process
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Migration
Positive Regulation Of Heterotypic Cell-cell Adhesion
Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin
Negative Regulation Of Anoikis
Angiogenesis
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cell-matrix Adhesion
Response To Ischemia
Double-strand Break Repair
Apoptotic Process
DNA Damage Response
Negative Regulation Of Microtubule Depolymerization
Endomitotic Cell Cycle
Cell Adhesion
Spermatogenesis
Spermatid Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Neuron Projection Development
Cell Differentiation
Platelet Formation
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Cytoplasmic Microtubule Organization
Positive Regulation Of Cell Adhesion Mediated By Integrin
Thrombopoietin-mediated Signaling Pathway
Regulation Of Cell Population Proliferation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Catalytic Activity
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cell Division
Regulation Of Cell Division
Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Cellular Response To Tumor Necrosis Factor
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Protein Targeting To Membrane
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Protein Localization To Plasma Membrane
Cellular Response To Nerve Growth Factor Stimulus
Positive Regulation Of Male Germ Cell Proliferation
Pathways
Fibronectin matrix formation
Cell surface interactions at the vascular wall
Neutrophil degranulation
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
GWAS
Serum carcinoembryonic antigen levels (
31666285
)
Interacting Genes
32 interacting genes:
APP
ASPG
CARTPT
CEACAM1
CEACAM5
CEACAM7
CEACAM8
CIB1
CSTF2
EXOC3L1
FOXH1
GCM2
GPANK1
HGS
HPCAL4
KANK2
MSS51
MYOZ1
PITX1
POM121
QRICH1
RHOXF2
SHC3
SMARCD1
TLX3
TNXB
UBQLN2
VENTX
VEZF1
WWOX
ZMYND19
ZNF76
38 interacting genes:
AURKB
CALCB
CD27
CDK4
CEACAM6
EIF4G1
ELAPOR1
EXOSC10
FEZ1
FUCA1
GLIS3
IFI6
ITGA2B
LSS
MAP3K5
NBR1
NCK2
NME4
NRIP1
ONECUT3
PAX3
PAX7
PLK2
PLK3
PRKDC
PSEN1
PSEN2
PTK2
RAC3
SCAF1
SSX7
TERT
TMEM95
TSGA10IP
UBR5
WAS
ZBTB49
ZDHHC17
Entrez ID
4680
10519
HPRD ID
01233
03800
Ensembl ID
ENSG00000086548
ENSG00000185043
Uniprot IDs
P40199
A0A140VK09
Q99828
PDB IDs
4WHC
4WTZ
4Y8A
4YIQ
1DGU
1DGV
1XO5
1Y1A
2L4H
2L4I
2LM5
6OCX
6OD0
Enriched GO Terms of Interacting Partners
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Response To Nerve Growth Factor
Cellular Response To Nerve Growth Factor Stimulus
Central Nervous System Development
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Developmental Process
Regulation Of Programmed Cell Death
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Kinetochore
Kinase Activity
Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Aspartic Endopeptidase Activity, Intramembrane Cleaving
Protein Binding
Protein Kinase Activity
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Translation In Response To Stress
Positive Regulation Of RNA Metabolic Process
Gamma-secretase Complex
Protein Serine Kinase Activity
Signal Complex Assembly
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Notch Receptor Processing
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Organelle Organization
Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Amyloid-beta Formation
Protein Serine/threonine Kinase Activity
Positive Regulation Of Intracellular Transport
Positive Regulation Of Biosynthetic Process
Dorsal/ventral Neural Tube Patterning
Regulation Of Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cellular Response To Stress
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Immune System Process
Regulation Of RNA Metabolic Process
T Cell Activation
Centrosome
Regulation Of Cellular Component Organization
Regulation Of DNA-templated Transcription
Negative Regulation Of CGAS/STING Signaling Pathway
Regulation Of RNA Biosynthetic Process
Mitotic G1/S Transition Checkpoint Signaling
Amyloid Precursor Protein Catabolic Process
Apoptotic Signaling Pathway
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Mitotic Cell Cycle
G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Anoikis
Maturation Of 5.8S RRNA
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