CEACAM6 and HPCAL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CEACAM6	HPCAL4
Description		CEA cell adhesion molecule 6	hippocalcin like 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Azurophil Granule Membrane Side Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Apoptotic Process Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis	Central Nervous System Development Response To Heat Regulation Of Signal Transduction
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Serum carcinoembryonic antigen levels ( 31666285)	Bone mineral density (Ward's triangle area) ( 27397699)
Interacting Genes		32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76	16 interacting genes: ANKRD33 AQP4 CDSN CEACAM6 DTX2 F3 FAM131C LITAF MSRA SCMH1 SPRED1 TEX13B TRPM5 TSC22D3 TTC12 UBE3A
Entrez ID		4680	51440
HPRD ID		01233	17113
Ensembl ID		ENSG00000086548	ENSG00000116983
Uniprot IDs		P40199	B4DGW9 Q9UM19
PDB IDs		4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?		Response To Nerve Growth Factor Cellular Response To Nerve Growth Factor Stimulus Central Nervous System Development Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Developmental Process
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