TCEA1 and RTF1

Number of citations of the paper that reports this interaction (PMID 20178742)
58

Data Source:
BioGRID (pull down)

		TCEA1	RTF1
Gene Name		transcription elongation factor A (SII), 1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleolus Cdc73/Paf1 Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Single-stranded DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Erythrocyte Differentiation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription	Negative Regulation Of Transcription From RNA Polymerase II Promoter Endodermal Cell Fate Commitment DNA-templated Transcription, Initiation Wnt Signaling Pathway Stem Cell Maintenance Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation
Pathways		Nucleotide Excision Repair Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Height ( 20881960)
Protein-Protein Interactions		17 interactors: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61	3 interactors: APP SRPK2 TCEA1
Entrez ID		6917	23168
HPRD ID		03252	11071
Ensembl ID		ENSG00000187735	ENSG00000137815
Uniprot IDs		B7Z4S1 P23193	Q92541
PDB IDs		1TFI 3NDQ	2BZE 2DB9 3U1U 4L1P 4L1U
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated MRNA Processing Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Histone H2B Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Cell Fate Commitment Involved In Formation Of Primary Germ Layer Positive Regulation Of Gene Expression MRNA Metabolic Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Endodermal Cell Differentiation RNA Processing Regulation Of Nitrogen Compound Metabolic Process Endoderm Formation Transcription Elongation From RNA Polymerase II Promoter Stem Cell Maintenance Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Myeloid Cell Differentiation Endoderm Development MRNA Polyadenylation Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Histone Ubiquitination RNA Polyadenylation Negative Regulation Of Cell Differentiation Stem Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Protein Monoubiquitination Regulation Of Histone Modification Wnt Signaling Pathway Formation Of Primary Germ Layer Positive Regulation Of Viral Transcription	Positive Regulation Of Viral Process Nuclear Speck Organization Regulation Of Viral Process Synaptic Growth At Neuromuscular Junction Positive Regulation Of Gene Expression Collateral Sprouting In Absence Of Injury Positive Regulation Of Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immune System Process Axon Choice Point Recognition MRNA Processing Neuron Remodeling MRNA Metabolic Process RNA Processing Cellular Copper Ion Homeostasis RNA Metabolic Process Positive Regulation Of Viral Genome Replication Copper Ion Homeostasis Suckling Behavior Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Stress Gene Expression Innate Immune Response Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Cycle RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Transcription From RNA Polymerase II Promoter System Development Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Viral Transcription Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Viral Genome Replication Regulation Of Cell Cycle G2/M Phase Transition Cellular Protein Metabolic Process Axon Cargo Transport Mating Neuromuscular Junction Development Regulation Of DNA-templated Transcription, Elongation Regulation Of RNA Metabolic Process
Tagcloud ?		arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5	aberrantly blastocyst compromising ctr9 document elf5 eomes fail fgf4 gata6 h3k36me3 imprinted imprinting inappropriate inappropriately meg3 mest nanog oct4 paf1 peg3 preimplantation reprogramming setd2 snrpn sox17 sox2 specification specify
Tagcloud (Difference) ?		arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5	aberrantly blastocyst compromising ctr9 document elf5 eomes fail fgf4 gata6 h3k36me3 imprinted imprinting inappropriate inappropriately meg3 mest nanog oct4 paf1 peg3 preimplantation reprogramming setd2 snrpn sox17 sox2 specification specify
Tagcloud (Intersection) ?