TCEA1 and WDR61

Number of citations of the paper that reports this interaction (PMID 20178742)
58

Data Source:
BioGRID (pull down)

		TCEA1	WDR61
Gene Name		transcription elongation factor A (SII), 1	WD repeat domain 61
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytoplasm Cdc73/Paf1 Complex Transcriptionally Active Chromatin Ski Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Erythrocyte Differentiation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription	Transcription, DNA-templated Wnt Signaling Pathway Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Histone H3-K79 Methylation
Pathways		Nucleotide Excision Repair Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61	7 interactors: ACVR1 BARD1 EZH2 SMURF1 TCEA1 TGFBR1 YWHAQ
Entrez ID		6917	80349
HPRD ID		03252	15236
Ensembl ID		ENSG00000187735	ENSG00000140395
Uniprot IDs		B7Z4S1 P23193	Q9GZS3
PDB IDs		1TFI 3NDQ	3OW8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated MRNA Processing Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Histone H2B Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Cell Fate Commitment Involved In Formation Of Primary Germ Layer Positive Regulation Of Gene Expression MRNA Metabolic Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Endodermal Cell Differentiation RNA Processing Regulation Of Nitrogen Compound Metabolic Process Endoderm Formation Transcription Elongation From RNA Polymerase II Promoter Stem Cell Maintenance Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Myeloid Cell Differentiation Endoderm Development MRNA Polyadenylation Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Histone Ubiquitination RNA Polyadenylation Negative Regulation Of Cell Differentiation Stem Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Protein Monoubiquitination Regulation Of Histone Modification Wnt Signaling Pathway Formation Of Primary Germ Layer Positive Regulation Of Viral Transcription	Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Pathway-restricted SMAD Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of RNA Metabolic Process Pharyngeal System Development Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Activin Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Peptidyl-threonine Phosphorylation Regulation Of DNA-templated Transcription, Elongation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Epithelial To Mesenchymal Transition Cell Cycle Process Cellular Response To Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signaling Regulation Of Intracellular Transport Regulation Of Transcription, DNA-templated BMP Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Endocardial Cushion Cell Fate Commitment Cell Cycle Regulation Of Metabolic Process Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Anatomical Structure Development Regulation Of Phosphorus Metabolic Process Cellular Response To Growth Factor Stimulus Mesenchymal Cell Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Regulation Of Cell Death Organ Development Positive Regulation Of Cell Death Negative Regulation Of MRNA 3'-end Processing Response To Stimulus
Tagcloud ?		arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Difference) ?		arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Intersection) ?