ZFYVE19 and MITD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFYVE19	MITD1
Description		zinc finger FYVE-type containing 19	microtubule interacting and trafficking domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Midbody Cleavage Furrow Flemming Body	Endosome Membrane Midbody Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Lipid Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Cytokinesis Mitotic Cytokinesis Checkpoint Signaling Cell Division Midbody Abscission	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Cell Division Midbody Abscission Multivesicular Body Sorting Pathway
Pathways
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061)	Bipolar disorder ( 21926972)
Interacting Genes		10 interacting genes: AXIN1 CAPN7 CCHCR1 DPY30 HTT MITD1 TRIM55 TRIM63 VPS4B ZDHHC17	17 interacting genes: ATF7 CARD10 CEBPA CHMP1A CHMP1B CHMP2A CHMP5 DSCAM GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655
Entrez ID		84936	129531
HPRD ID		15731	14044
Ensembl ID		ENSG00000166140	ENSG00000158411
Uniprot IDs		Q96K21	Q8WV92
PDB IDs			2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Mitotic Cytokinetic Process Viral Budding Viral Budding Via Host ESCRT Complex Midbody Abscission Cytokinetic Process Intracellular Transport Multivesicular Body Sorting Pathway P53 Binding Cellular Localization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Localization In Cell Beta-catenin Destruction Complex Assembly Axial Mesoderm Formation Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Late Endosomal Microautophagy Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Organelle Assembly Canonical Wnt Signaling Pathway Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of CAMKK-AMPK Signaling Cascade MIT Domain Binding	Mitotic Cytokinetic Process Midbody Abscission ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole ESCRT III Complex Disassembly ESCRT Complex Disassembly Cytokinetic Process Multivesicular Body-lysosome Fusion Viral Budding From Plasma Membrane Lysosomal Membrane Organization Regulation Of Centrosome Cycle Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Viral Budding Nuclear Membrane Reassembly Multivesicular Body Membrane Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Regulation Of Spindle Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Mitotic Metaphase Chromosome Alignment Multivesicular Body Sorting Pathway Regulation Of Centrosome Duplication Nuclear Membrane Organization Autophagosome Maturation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Autophagosome Membrane Metaphase Chromosome Alignment Membrane Assembly Midbody Chromosome Localization Endosome Organization Nuclear Pore Nucleus Organization Vesicle Fusion Organelle Membrane Fusion Regulation Of Microtubule-based Process Plasma Membrane Organization Lysosomal Transport
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