SCAMP1 and SNAP23

Number of citations of the paper that reports this interaction (PubMedID 12124380)
0

Data Source:
HPRD (in vivo)

		SCAMP1	SNAP23
Description		secretory carrier membrane protein 1	synaptosome associated protein 23
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Zymogen Granule Membrane Synapse Recycling Endosome Membrane	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Cilium Membrane Phagocytic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Synapse Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	Protein Binding Protein Domain Specific Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Endocytosis Protein Transport Establishment Of Localization In Cell	Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Membrane Fusion
Pathways		Neutrophil degranulation	ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339) Intraocular pressure ( 29785010) Platelet count ( 32888494) Plateletcrit ( 32888494) Triglycerides ( 26780889)	Bipolar disorder ( 31043756)
Interacting Genes		27 interacting genes: ARFIP1 ARFIP2 CFTR EGFR EPS15 GAD2 ITSN1 KRTAP13-1 MTERF3 NDRG4 PBX3 PCYT1A PTPN9 SCAMP2 SLC9A7 SNAP23 SNAP25 SNCA SPG21 SYNRG TASOR2 TBRG4 THAP4 TP53 TTPA UBE3A ZMIZ2	32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		9522	8773
HPRD ID		06072	03962
Ensembl ID		ENSG00000085365	ENSG00000092531
Uniprot IDs		A0A087WXB0 B4E2V7 O15126	A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Priming Regulation Of Golgi Lumen Acidification Cytosol Vesicle-mediated Transport In Synapse Exocytosis Import Into Cell Regulation Of Protein Localization Establishment Of Localization In Cell Postsynaptic Endocytic Zone Vesicle Docking Establishment Of Protein Localization Embryonic Organ Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Endosome Positive Regulation Of Receptor Recycling Organelle Localization By Membrane Tethering Positive Regulation Of Protein Localization To Cell Periphery Protein Transport Locomotory Behavior Synaptic Vesicle Membrane Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cellular PH Membrane Docking Regulation Of Intracellular PH Vesicle-mediated Transport Secretion By Cell Intracellular Vesicle Regulation Of PH Recycling Endosome Membrane Post-Golgi Vesicle-mediated Transport Positive Regulation Of Protein Localization Endocytosis Regulation Of Receptor Recycling Embryonic Placenta Development Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Trans-Golgi Network Membrane Regulation Of Arp2/3 Complex-mediated Actin Nucleation Golgi Apparatus Neurotransmitter Uptake Phospholipid Binding Phosphatidylinositol-4-phosphate Binding 14-3-3 Protein Binding Regulation Of Cellular Localization Recycling Endosome Positive Regulation Of Signaling Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Multivesicular Body, Internal Vesicle Lumen	SNARE Complex SNAP Receptor Activity Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion SNARE Binding Exocytosis Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Protein Transport Establishment Of Protein Localization Vesicle-mediated Transport Secretion By Cell Vesicle Organization Secretion Membrane Organization Establishment Of Localization In Cell Intracellular Protein Localization SNARE Complex Assembly Syntaxin Binding Organelle Localization Intracellular Protein Transport Regulation Of Exocytosis Cellular Localization Intracellular Transport Regulation Of Synaptic Vesicle Priming Regulation Of Vesicle-mediated Transport Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Secretion By Cell Regulated Exocytosis Calcium-ion Regulated Exocytosis Endomembrane System Regulation Of Secretion Zymogen Granule Membrane Phagocytic Vesicle Positive Regulation Of Exocytosis Neutrophil Degranulation Regulation Of Histamine Secretion By Mast Cell Vesicle-mediated Transport In Synapse Neuron Projection Recycling Endosome Membrane Secretory Granule Regulation Of Hormone Secretion Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Exocytosis Synaptic Vesicle Membrane
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