SCAMP1 and ZMIZ2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SCAMP1	ZMIZ2
Description		secretory carrier membrane protein 1	zinc finger MIZ-type containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Zymogen Granule Membrane Synapse Recycling Endosome Membrane	Chromatin Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork
	Molecular Function	Protein Binding Protein Domain Specific Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding SUMO Ligase Activity
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Endocytosis Protein Transport Establishment Of Localization In Cell	Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II SMAD Protein Signal Transduction
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339) Intraocular pressure ( 29785010) Platelet count ( 32888494) Plateletcrit ( 32888494) Triglycerides ( 26780889)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Fasting glucose ( 34059833) General cognitive ability ( 29844566) Hematocrit ( 32888494) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		27 interacting genes: ARFIP1 ARFIP2 CFTR EGFR EPS15 GAD2 ITSN1 KRTAP13-1 MTERF3 NDRG4 PBX3 PCYT1A PTPN9 SCAMP2 SLC9A7 SNAP23 SNAP25 SNCA SPG21 SYNRG TASOR2 TBRG4 THAP4 TP53 TTPA UBE3A ZMIZ2	27 interacting genes: AKAP19 AR ARSJ ASB13 BANP CPNE7 CRCP FRS3 GCM2 INTS4 KPNA4 LRRC37A11P MCPH1 MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELENOV SOCS6 SS18L1 SSX2 SUMO2 TP53 TRAPPC6A
Entrez ID		9522	83637
HPRD ID		06072	13225
Ensembl ID		ENSG00000085365	ENSG00000122515
Uniprot IDs		A0A087WXB0 B4E2V7 O15126	E7EWM3 Q8NF64
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Priming Regulation Of Golgi Lumen Acidification Cytosol Vesicle-mediated Transport In Synapse Exocytosis Import Into Cell Regulation Of Protein Localization Establishment Of Localization In Cell Postsynaptic Endocytic Zone Vesicle Docking Establishment Of Protein Localization Embryonic Organ Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Endosome Positive Regulation Of Receptor Recycling Organelle Localization By Membrane Tethering Positive Regulation Of Protein Localization To Cell Periphery Protein Transport Locomotory Behavior Synaptic Vesicle Membrane Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cellular PH Membrane Docking Regulation Of Intracellular PH Vesicle-mediated Transport Secretion By Cell Intracellular Vesicle Regulation Of PH Recycling Endosome Membrane Post-Golgi Vesicle-mediated Transport Positive Regulation Of Protein Localization Endocytosis Regulation Of Receptor Recycling Embryonic Placenta Development Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Trans-Golgi Network Membrane Regulation Of Arp2/3 Complex-mediated Actin Nucleation Golgi Apparatus Neurotransmitter Uptake Phospholipid Binding Phosphatidylinositol-4-phosphate Binding 14-3-3 Protein Binding Regulation Of Cellular Localization Recycling Endosome Positive Regulation Of Signaling Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Multivesicular Body, Internal Vesicle Lumen	Postsynaptic Cytosol
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