PCYT1B and KIAA0368

Number of citations of the paper that reports this interaction (PMID 20682791)
15

Data Source:
BioGRID (two hybrid)

		PCYT1B	KIAA0368
Gene Name		phosphate cytidylyltransferase 1, choline, beta	KIAA0368
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane	Proteasome Complex Nucleus Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane Cytoplasmic Membrane-bounded Vesicle ER To Golgi Transport Vesicle Endocytic Vesicle
	Molecular Function	Choline-phosphate Cytidylyltransferase Activity	Molecular_function
	Biological Process	Ovarian Follicle Development Phospholipid Metabolic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Spermatogenesis Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	ER-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		Synthesis of PC Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis
Drugs		Choline
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ACTA1 ACTA2 APP KIAA0368 PAXIP1	28 interactors: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREML GOLGB1 HNRNPM MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		9468	23392
HPRD ID		05376	11078
Ensembl ID		ENSG00000102230	ENSG00000136813
Uniprot IDs		Q9Y5K3	J3KN16 Q5VYK3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H3-K36 Methylation Cell Growth Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Muscle Contraction Response To Abiotic Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Connective Tissue Development Organ Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Glomerular Mesangial Cell Development Muscle System Process Axon Choice Point Recognition Skeletal Muscle Thin Filament Assembly Mesangial Cell Development Renal Interstitial Fibroblast Development Skeletal Myofibril Assembly Chorion Development Neuron Remodeling Skeletal Muscle Adaptation Cell Differentiation Movement Of Cell Or Subcellular Component Vascular Smooth Muscle Contraction Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Response To Radiation Tissue Development Positive Regulation Of DNA-templated Transcription, Initiation Cellular Copper Ion Homeostasis Cell Development Response To External Stimulus Growth System Development Regulation Of Cellular Ketone Metabolic Process Blood Vessel Development Positive Regulation Of Histone Acetylation Regulation Of DNA-templated Transcription, Initiation Glomerulus Vasculature Development Copper Ion Homeostasis Suckling Behavior Vasculature Development Regulation Of Histone H3-K4 Methylation Skeletal Muscle Fiber Development Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Isotype Switching Positive Regulation Of Protein Acetylation	ER-associated Ubiquitin-dependent Protein Catabolic Process Nucleus Localization Cell Cycle Establishment Of Nucleus Localization Cell Cycle Process Positive Regulation Of DNA Repair Cell Division Endomembrane System Organization Negative Regulation Of Muscle Cell Differentiation Histone H2A-K13 Ubiquitination Protein Localization To T-tubule Histone H2A-K15 Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of DNA Repair Histone H2A K63-linked Ubiquitination T-tubule Organization Protein Localization To M-band Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Response To DNA Damage Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process
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