PCYT1B and ACTA2

Number of citations of the paper that reports this interaction (PMID 11580270)
13

Data Source:
HPRD (in vitro)

		PCYT1B	ACTA2
Gene Name		phosphate cytidylyltransferase 1, choline, beta	actin, alpha 2, smooth muscle, aorta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane	Extracellular Space Cytoplasm Cytosol Actin Cytoskeleton Smooth Muscle Contractile Fiber Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Choline-phosphate Cytidylyltransferase Activity	ATP Binding Protein Kinase Binding
	Biological Process	Ovarian Follicle Development Phospholipid Metabolic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Spermatogenesis Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	Muscle Contraction Regulation Of Blood Pressure Response To Virus Vascular Smooth Muscle Contraction Glomerular Mesangial Cell Development
Pathways		Synthesis of PC Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis	Smooth Muscle Contraction
Drugs		Choline
Diseases
GWAS			Immunoglobulin A ( 20694011)
Protein-Protein Interactions		5 interactors: ACTA1 ACTA2 APP KIAA0368 PAXIP1	16 interactors: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SHBG SNTA1 TMSB4X YBX1
Entrez ID		9468	59
HPRD ID		05376	00031
Ensembl ID		ENSG00000102230	ENSG00000107796
Uniprot IDs		Q9Y5K3	D2JYH4 P62736
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H3-K36 Methylation Cell Growth Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Muscle Contraction Response To Abiotic Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Connective Tissue Development Organ Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Glomerular Mesangial Cell Development Muscle System Process Axon Choice Point Recognition Skeletal Muscle Thin Filament Assembly Mesangial Cell Development Renal Interstitial Fibroblast Development Skeletal Myofibril Assembly Chorion Development Neuron Remodeling Skeletal Muscle Adaptation Cell Differentiation Movement Of Cell Or Subcellular Component Vascular Smooth Muscle Contraction Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Response To Radiation Tissue Development Positive Regulation Of DNA-templated Transcription, Initiation Cellular Copper Ion Homeostasis Cell Development Response To External Stimulus Growth System Development Regulation Of Cellular Ketone Metabolic Process Blood Vessel Development Positive Regulation Of Histone Acetylation Regulation Of DNA-templated Transcription, Initiation Glomerulus Vasculature Development Copper Ion Homeostasis Suckling Behavior Vasculature Development Regulation Of Histone H3-K4 Methylation Skeletal Muscle Fiber Development Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Isotype Switching Positive Regulation Of Protein Acetylation	N-terminal Peptidyl-lysine Acetylation Regulation Of Actin Filament-based Process N-terminal Protein Amino Acid Acetylation Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein Dephosphorylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Blood Coagulation N-terminal Protein Amino Acid Modification Hemostasis Negative Regulation Of Cytoskeleton Organization Regulation Of Cellular Response To Heat Platelet Activation Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Toxin Transport Binding Of Sperm To Zona Pellucida Positive Regulation Of Dephosphorylation Regulation Of Body Fluid Levels Sperm-egg Recognition Wound Healing Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of MAPK Cascade Regulation Of DNA-templated Transcription In Response To Stress Muscle System Process 'de Novo' Posttranslational Protein Folding Actin Filament-based Process Histone H2B Acetylation Positive Regulation Of Phospholipid Scramblase Activity Skeletal Muscle Hypertrophy Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process ERBB2-ERBB3 Signaling Pathway Regulation Of Vasoconstriction By Circulating Norepinephrine Primary Spermatocyte Growth 'de Novo' Protein Folding Developmental Process Cellular Response To Heat Cell Activation Cell-cell Recognition Termination Of Signal Transduction Response To Wounding Rhythmic Process Platelet Degranulation Negative Regulation Of Actin Filament Polymerization Regulation Of Cellular Component Size Positive Regulation Of Type I Interferon Production Positive Regulation Of Phospholipid Catabolic Process Glucosylceramide Catabolic Process ERBB2 Signaling Pathway
Tagcloud ?			attaining buffalo calves cirbp cryopreservation cryopreserved cyp11a1 d20s20 dairies dimethylsulfoxide dismutase2 dmso fbs fcc freezing germplasm homeobox leydig maturity pou pou5f1 protein3 rbm3 sod2 subfamily surviving testicular uncontrolled vim
Tagcloud (Difference) ?			attaining buffalo calves cirbp cryopreservation cryopreserved cyp11a1 d20s20 dairies dimethylsulfoxide dismutase2 dmso fbs fcc freezing germplasm homeobox leydig maturity pou pou5f1 protein3 rbm3 sod2 subfamily surviving testicular uncontrolled vim
Tagcloud (Intersection) ?