PICK1 and ARF3

Number of citations of the paper that reports this interaction (PMID 10623590)
8

Data Source:
HPRD (two hybrid)

		PICK1	ARF3
Gene Name		protein interacting with PRKCA 1	ADP-ribosylation factor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Cytoskeleton Plasma Membrane Cell Junction Endocytic Vesicle Membrane Presynaptic Membrane Neuron Projection Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Neuronal Postsynaptic Density	Golgi Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	G-protein Coupled Receptor Binding Protein Kinase C Binding Receptor Binding Protein Binding Protein C-terminus Binding ATPase Activity Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding Actin Filament Binding Arp2/3 Complex Binding	GTPase Activity GTP Binding
	Biological Process	Positive Regulation Of Receptor Internalization Protein Phosphorylation Protein Targeting Retrograde Vesicle-mediated Transport, Golgi To ER Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Monoamine Transport Glial Cell Development Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Decreased Oxygen Levels Cellular Response To Glucose Starvation DNA Methylation Involved In Embryo Development DNA Methylation Involved In Gamete Generation Receptor Clustering Neuronal Ion Channel Clustering Long Term Synaptic Depression Dendritic Spine Organization Dendritic Spine Maintenance	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Small Molecule Metabolic Process
Pathways		Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses	Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: APTX AQP1 ARF1 ARF3 ASIC1 ASIC2 ATXN1L ATXN3 ATXN7 ATXN7L3 BTG2 CIC COIL CTNNB1 EFNB1 EFNB2 EHD2 EPHB2 ERBB2 ERBB2IP F11R FXN GFI1 GFI1B GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIP1 GRM3 GRM7 JAM3 LRP2BP MLLT4 PARK2 PRKCA PRKCG PRLHR PVRL2 PVRL4 SACS SLC6A3 UBQLN4 USP7	9 interactors: ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 KIF23 PICK1 SLC2A4
Entrez ID		9463	377
HPRD ID		16176	00056
Ensembl ID		ENSG00000100151	ENSG00000134287
Uniprot IDs		B3KS52 Q9NRD5	B7ZB63 P61204
PDB IDs		2GZV
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Cellular Response To Stimulus Regulation Of Cellular Process Response To Stimulus Signaling Cell Communication Behavior Regulation Of Synaptic Transmission Single-organism Behavior Neurological System Process Negative Regulation Of Synaptic Transmission Regulation Of Synaptic Transmission, Glutamatergic Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Glutamate Receptor Signaling Pathway Anatomical Structure Development Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Nervous System Development Negative Regulation Of Synaptic Transmission, Glutamatergic Cell Junction Assembly Developmental Process Ion Transport Cell-cell Junction Organization Ion Transmembrane Transport G-protein Coupled Glutamate Receptor Signaling Pathway Histone Deubiquitination Learning Or Memory Negative Regulation Of Adenylate Cyclase Activity Multicellular Organismal Development Regulation Of Body Fluid Levels Negative Regulation Of Lyase Activity Establishment Of Endothelial Barrier Cognition Response To External Stimulus System Development Regulation Of Signaling Adherens Junction Organization Multicellular Organismal Response To Stress Negative Regulation Of CAMP Biosynthetic Process Cellular Process Negative Regulation Of CAMP Metabolic Process Sensory Perception Of Sour Taste Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Death Negative Regulation Of Programmed Cell Death	Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Amylopectin Biosynthetic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Localization Vesicle-mediated Transport Mitotic Spindle Midzone Assembly Positive Regulation Of Protein Catabolic Process Mitotic Spindle Elongation DNA Methylation Involved In Embryo Development Glucose Import Dendritic Spine Maintenance Transport Spindle Midzone Assembly Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Toxin Metabolic Process Negative Regulation Of Actin Nucleation Long Term Synaptic Depression
Tagcloud ?		altering ampa calsyntenin clarified confirming coordinated deprivation elicited excitotoxic glua1 glun2a glun2b glun3a grip1 hippocampal insults ionotropic ischemia ogd profound proteome repression sapap2 snap submitted synaptic tarpgamma3 transcriptome vulnerability	abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative
Tagcloud (Difference) ?		altering ampa calsyntenin clarified confirming coordinated deprivation elicited excitotoxic glua1 glun2a glun2b glun3a grip1 hippocampal insults ionotropic ischemia ogd profound proteome repression sapap2 snap submitted synaptic tarpgamma3 transcriptome vulnerability	abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative
Tagcloud (Intersection) ?