PICK1 and BTG2

Number of citations of the paper that reports this interaction (PMID 11237868)
4

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		PICK1	BTG2
Gene Name		protein interacting with PRKCA 1	BTG family, member 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Cytoskeleton Plasma Membrane Cell Junction Endocytic Vesicle Membrane Presynaptic Membrane Neuron Projection Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Neuronal Postsynaptic Density	Extracellular Vesicular Exosome
	Molecular Function	G-protein Coupled Receptor Binding Protein Kinase C Binding Receptor Binding Protein Binding Protein C-terminus Binding ATPase Activity Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding Actin Filament Binding Arp2/3 Complex Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Protein Phosphorylation Protein Targeting Retrograde Vesicle-mediated Transport, Golgi To ER Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Monoamine Transport Glial Cell Development Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Decreased Oxygen Levels Cellular Response To Glucose Starvation DNA Methylation Involved In Embryo Development DNA Methylation Involved In Gamete Generation Receptor Clustering Neuronal Ion Channel Clustering Long Term Synaptic Depression Dendritic Spine Organization Dendritic Spine Maintenance	DNA Repair Transcription, DNA-templated Protein Methylation Cellular Response To DNA Damage Stimulus Negative Regulation Of Cell Proliferation Associative Learning Response To Mechanical Stimulus Anterior/posterior Pattern Specification Response To Organic Cyclic Compound Negative Regulation Of Translation Dentate Gyrus Development Central Nervous System Neuron Development Neuron Projection Development Skeletal Muscle Cell Differentiation Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Electrical Stimulus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Neural Precursor Cell Proliferation
Pathways		Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: APTX AQP1 ARF1 ARF3 ASIC1 ASIC2 ATXN1L ATXN3 ATXN7 ATXN7L3 BTG2 CIC COIL CTNNB1 EFNB1 EFNB2 EHD2 EPHB2 ERBB2 ERBB2IP F11R FXN GFI1 GFI1B GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIP1 GRM3 GRM7 JAM3 LRP2BP MLLT4 PARK2 PRKCA PRKCG PRLHR PVRL2 PVRL4 SACS SLC6A3 UBQLN4 USP7	13 interactors: CNOT7 CNOT8 DYT10 HMGN1 HOXB9 HOXC8 PICK1 PRKCA PRMT1 SKP2 SMAD1 SMAD9 SRA1
Entrez ID		9463	7832
HPRD ID		16176	03357
Ensembl ID		ENSG00000100151	ENSG00000159388
Uniprot IDs		B3KS52 Q9NRD5	P78543
PDB IDs		2GZV	3DJU 3E9V
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Cellular Response To Stimulus Regulation Of Cellular Process Response To Stimulus Signaling Cell Communication Behavior Regulation Of Synaptic Transmission Single-organism Behavior Neurological System Process Negative Regulation Of Synaptic Transmission Regulation Of Synaptic Transmission, Glutamatergic Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Glutamate Receptor Signaling Pathway Anatomical Structure Development Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Nervous System Development Negative Regulation Of Synaptic Transmission, Glutamatergic Cell Junction Assembly Developmental Process Ion Transport Cell-cell Junction Organization Ion Transmembrane Transport G-protein Coupled Glutamate Receptor Signaling Pathway Histone Deubiquitination Learning Or Memory Negative Regulation Of Adenylate Cyclase Activity Multicellular Organismal Development Regulation Of Body Fluid Levels Negative Regulation Of Lyase Activity Establishment Of Endothelial Barrier Cognition Response To External Stimulus System Development Regulation Of Signaling Adherens Junction Organization Multicellular Organismal Response To Stress Negative Regulation Of CAMP Biosynthetic Process Cellular Process Negative Regulation Of CAMP Metabolic Process Sensory Perception Of Sour Taste Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Death Negative Regulation Of Programmed Cell Death	Gene Silencing By MiRNA Posttranscriptional Gene Silencing Regulation Of Gene Expression, Epigenetic Gene Silencing By RNA Skeletal System Development Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Gene Silencing Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Cell Proliferation Transcription, DNA-templated Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of MRNA Catabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Heterocycle Metabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening Cellular Aromatic Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Cartilage Development Regulation Of Transcription From RNA Polymerase II Promoter RNA Processing Developmental Process Nitrogen Compound Metabolic Process Connective Tissue Development System Development Negative Regulation Of Cell Proliferation Regulation Of Cellular Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Cell Proliferation Multicellular Organismal Development Positive Regulation Of Gene Expression BMP Signaling Pathway Cellular Macromolecule Biosynthetic Process Anatomical Structure Development
Tagcloud ?		altering ampa calsyntenin clarified confirming coordinated deprivation elicited excitotoxic glua1 glun2a glun2b glun3a grip1 hippocampal insults ionotropic ischemia ogd profound proteome repression sapap2 snap submitted synaptic tarpgamma3 transcriptome vulnerability	abolished androgen ar attenuated attenuates cisplatin directed dosage element expressions fragment ggaaaggaa ggaaagtcc gggcacc gggcagagccc go lncap mutagenesis nfkappab null p53 partly pc prostate psa repressed treatments upregulation upstream
Tagcloud (Difference) ?		altering ampa calsyntenin clarified confirming coordinated deprivation elicited excitotoxic glua1 glun2a glun2b glun3a grip1 hippocampal insults ionotropic ischemia ogd profound proteome repression sapap2 snap submitted synaptic tarpgamma3 transcriptome vulnerability	abolished androgen ar attenuated attenuates cisplatin directed dosage element expressions fragment ggaaaggaa ggaaagtcc gggcacc gggcagagccc go lncap mutagenesis nfkappab null p53 partly pc prostate psa repressed treatments upregulation upstream
Tagcloud (Intersection) ?