KIF17 and FHL5

Number of citations of the paper that reports this interaction (PMID 12493914)
23

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		KIF17	FHL5
Gene Name		kinesin family member 17	four and a half LIM domains 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Primary Cilium Periciliary Membrane Compartment	Nucleus
	Molecular Function	ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	Transcription Coactivator Activity Protein Binding Zinc Ion Binding
	Biological Process	Organelle Organization Microtubule-based Movement Metabolic Process Protein Transport Vesicle-mediated Transport Neurogenesis Cell Projection Organization Protein Complex Localization	Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS			Coronary heart disease ( 22319020) Migraine ( 22683712)
Protein-Protein Interactions		7 interactors: APBA1 C16orf70 FHL5 GFI1B MAP3K10 MAP3K11 XPO1	12 interactors: COIL CREB1 CREM DNAL4 FHL2 FHL3 HOXA1 KIF17 SMAD1 SRF STX11 ZNF446
Entrez ID		57576	9457
HPRD ID		10388	05497
Ensembl ID		ENSG00000117245	ENSG00000112214
Uniprot IDs		Q9P2E2	Q5TD97
PDB IDs			1X68
Enriched GO Terms of Interacting Partners?		Activation Of JNKK Activity Activation Of JUN Kinase Activity Activation Of MAPKK Activity Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of JNK Cascade Ribosomal Small Subunit Export From Nucleus Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Metabolic Process Gamma-aminobutyric Acid Secretion Regulation Of Metabolic Process Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity MAPK Cascade Negative Regulation Of Transcription, DNA-templated Ribosomal Large Subunit Export From Nucleus Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Activation Of Protein Kinase Activity Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Ribosomal Subunit Export From Nucleus Gamma-aminobutyric Acid Transport Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Regulation Of Histone H3-K4 Methylation Positive Regulation Of Kinase Activity Glutamate Secretion Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transferase Activity Protein Export From Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Centrosome Duplication Positive Regulation Of Cell Death	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Heart Trabecula Formation RNA Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Heart Trabecula Morphogenesis Cardiac Muscle Tissue Development RNA Metabolic Process Tube Development Trabecula Morphogenesis Multicellular Organismal Development Cell Differentiation Gene Expression Cognition Brain Development Artery Morphogenesis Striated Muscle Tissue Development Cellular Macromolecule Biosynthetic Process Head Development Macromolecule Biosynthetic Process Muscle Tissue Development Artery Development Positive Regulation Of Cellular Metabolic Process Cardiac Muscle Cell Development Cardiovascular System Development Transcription From RNA Polymerase II Promoter Abducens Nerve Formation Contractile Actin Filament Bundle Assembly Optokinetic Behavior Neurogenesis Developmental Process Mesoderm Formation Central Nervous System Development Mesoderm Morphogenesis System Development Cellular Response To Organic Substance Facial Nucleus Development Anatomical Structure Formation Involved In Morphogenesis Regulation Of Transcription, DNA-templated Single-organism Behavior Organ Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Pattern Specification Process Cardiac Muscle Cell Differentiation
Tagcloud ?		calmodulin camk cargo compartments complexity confinement conversely dendrites dendritic distances dramatically exits kinesin locally mobile nascent processed regimes restricts scales secretory segments spatial spatially tight trafficking transported tuned zones	1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp atp5b c7orf10 candidate fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide
Tagcloud (Difference) ?		calmodulin camk cargo compartments complexity confinement conversely dendrites dendritic distances dramatically exits kinesin locally mobile nascent processed regimes restricts scales secretory segments spatial spatially tight trafficking transported tuned zones	1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp atp5b c7orf10 candidate fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide
Tagcloud (Intersection) ?