KIF17

Description		kinesin family member 17
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Microtubule Organizing Center Cytosol Cytoskeleton Kinesin Complex Microtubule Cilium Axoneme Microtubule Cytoskeleton Dendrite Photoreceptor Connecting Cilium Dendrite Cytoplasm Ciliary Basal Body Cell Projection Neuron Projection Postsynapse Periciliary Membrane Compartment
	Molecular Function	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity
	Biological Process	Microtubule-based Process Microtubule-based Movement Protein Transport Vesicle-mediated Transport Cell Projection Organization Protein-containing Complex Localization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex
Pathways		Intraflagellar transport Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Ceramide levels (C24:0) ( 32489964) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Type 1 diabetes (age at diagnosis) ( 33179336)
Interacting Genes		8 interacting genes: APBA1 FHL5 FXR1 GFI1B MAP3K10 MAP3K11 PHAF1 XPO1
Entrez ID		57576
HPRD ID		10388
Ensembl ID		ENSG00000117245
Uniprot IDs		A0A0A0MRS8 Q9P2E2
PDB IDs
Enriched GO Terms of Interacting Partners?		JUN Kinase Kinase Kinase Activity Positive Regulation Of JUN Kinase Activity MAP Kinase Kinase Kinase Activity Positive Regulation Of MAP Kinase Activity Presynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Protein Serine/threonine Kinase Activity JNK Cascade Regulation Of MAP Kinase Activity Cellular Localization Dendritic Spine Regulation Of Macromolecule Metabolic Process Gamma-aminobutyric Acid Secretion Positive Regulation Of Kinase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Kinase Activity Negative Regulation Of RNA Metabolic Process Protein Autophosphorylation Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of JNK Cascade Protein Homodimerization Activity Regulation Of JNK Cascade Regulation Of Protein Metabolic Process Annulate Lamellae Cellular Response To Salt Ribosomal Small Subunit Export From Nucleus Response To Triglyceride Ribosomal Large Subunit Export From Nucleus MRNA Transport Cellular Response To Triglyceride RNA Transport RNA Strand Annealing Activity Nuclear Pore Localization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Intracellular Membraneless Organelle Regulation Of Metabolic Process Nucleobase-containing Compound Transport Nuclear Envelope Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Phosphorylation MAPK Cascade Mitogen-activated Protein Kinase Kinase Binding Nuclear Export Signal Receptor Activity Ribosomal Subunit Export From Nucleus Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Nuclear Pore Complex Assembly Positive Regulation Of Phosphorylation Regulation Of Kinase Activity
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