RAB26 and OIP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RAB26	OIP5
Description		RAB26, member RAS oncogene family	Opa interacting protein 5
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GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Plasma Membrane Membrane Transport Vesicle Membrane Secretory Granule Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Chromocenter Cajal Body Nuclear Speck CENP-A Recruiting Complex
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GMP Binding Metal Ion Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Protein Transport Regulation Of Exocytosis Exocrine System Development Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Regulation Protein Catabolic Process At Presynapse	Chromosome Segregation Cell Communication CENP-A Containing Chromatin Assembly Cell Division Pericentric Heterochromatin Organization
Pathways		RAB geranylgeranylation	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Ulcerative colitis ( 28067908)
Interacting Genes		8 interacting genes: APP FHL5 GCH1 KRT33B OIP5 RIMS1 SNCA UNKL	142 interacting genes: A1CF ABI2 ABI3 ABL2 AGXT BCAS2 BEX2 BFSP2 BLOC1S5 BRAF C1orf94 C21orf91 C7orf57 CASP10 CBY2 CCDC22 CCDC24 CCHCR1 CDR2L CEP57 CERK CHCHD2 CIMIP1 COX5B CRACR2A CTNNA3 DMRT3 DTNBP1 DTX2 DUSP21 EFHC1 EIF4ENIF1 ESS2 FAM161B FAM222B FOXJ1 FSD2 GADD45GIP1 GCC1 GEM GLIS2 GPANK1 GPS2 HAPLN2 HGS HJURP HOXB5 HOXB9 HOXC8 HSF4 IL16 KANK2 KDM1A KIF9 KLHL38 KLHL42 KNSTRN KRT14 KRT15 KRT27 KRT3 KRT35 KRT37 KRT40 KRT6B KRT75 KRT81 KRT83 KRT86 KRTAP13-2 KRTAP19-5 KRTAP19-6 LENG1 MECOM MED4 MEIS2 MGAT5B MIIP MIS18A MIS18BP1 MISP MORN3 MYEF2 MYRIP NDUFAB1 NECAB2 NUP54 NUP62 P4HA3 PATZ1 PEX19 PHETA1 PITX2 PLAGL2 POLR2J POU6F2 PRR35 PSMB1 RAB26 RABGEF1 RAF1 RARG RIBC1 RUNX1T1 RUSC1 S100Z SAMD7 SAXO1 SAXO4 SHISA6 SKIL SMARCE1 SNRNP25 SNRPB SOHLH1 SORBS3 SPATA24 SPMIP4 SYCE1L TEKT3 TEX12 TFAP2D TFIP11 TIMM8A TLX3 TMPO TPM3 TPRX1 TRIB3 TRIM73 TRIP6 TROAP TSSK3 USHBP1 USP2 USP54 WASHC1 YTHDF1 ZIC1 ZMAT1 ZNF417 ZNF655
Entrez ID		25837	11339
HPRD ID		05676	09352
Ensembl ID		ENSG00000167964	ENSG00000104147
Uniprot IDs		Q9ULW5	O43482
PDB IDs		2G6B	7SFY
Enriched GO Terms of Interacting Partners?		Regulation Of Presynapse Organization Response To Copper Ion Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Presynapse Assembly Amyloid Fibril Formation Regulation Of Superoxide Metabolic Process Regulation Of Neurotransmitter Uptake Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Cellular Response To Copper Ion Catecholamine Biosynthetic Process Biogenic Amine Biosynthetic Process Dopamine Biosynthetic Process Dopamine Metabolic Process Synaptic Vesicle Priming Synaptic Vesicle Exocytosis Metal Ion Binding Amine Biosynthetic Process Synapse Organization Catecholamine Metabolic Process Modulation Of Excitatory Postsynaptic Potential Amyloid-beta Complex Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Macrophage Activation Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Biogenic Amine Metabolic Process GTP Cyclohydrolase I Activity Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Amine Metabolic Process Adult Locomotory Behavior Response To Interleukin-1 Phenol-containing Compound Metabolic Process Regulation Of Neurotransmitter Secretion Zinc Ion Binding Acetylcholine Receptor Activator Activity Regulation Of Membrane Potential Protein Tetramerization Lipoprotein Particle Positive Regulation Of Protein Import Response To Type II Interferon	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Keratin Filament Protein Binding Supramolecular Fiber Organization Cytoskeleton Axonemal A Tubule Inner Sheath Cytoskeleton Organization Structural Molecule Activity Organelle Organization Sperm Flagellum Keratinization Motile Cilium CENP-A Containing Chromatin Assembly Pericentric Heterochromatin Organization CENP-A Recruiting Complex
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