HOMER1 and TANC1

Number of citations of the paper that reports this interaction (PubMedID 15673434)
0

Data Source:
HPRD (in vitro, in vivo)

		HOMER1	TANC1
Description		homer scaffold protein 1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Membrane Z Disc Axon Dendrite Cell Projection Neuron Projection Costamere Dendritic Spine Neuron Spine Apical Part Of Cell Synapse Postsynapse Glutamatergic Synapse Postsynaptic Cytosol	Postsynaptic Density Dendrite Neuronal Cell Body Axon Terminus Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Signaling Adaptor Activity Transmembrane Transporter Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Positive Regulation Of Signal Transduction Behavioral Response To Cocaine Skeletal Muscle Fiber Development Protein Tetramerization Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Calcium Ion Import Regulation Of Dendritic Spine Maintenance Regulation Of Store-operated Calcium Entry	Myoblast Fusion Visual Learning Dendritic Spine Maintenance Regulation Of Postsynapse Organization
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756 34002096) Blood and toenail selenium levels ( 25343990) Cryptococcosis in HIV infection ( 33269293) Height ( 18193045) Hepcidin/ferritin ratio ( 27846281) Lateral ventricle temporal horn volume ( 31530798) Major depressive disorder ( 20673876) Metabolite levels ( 23823483) Toenail selenium levels ( 25343990)	Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 28869591 30598549) Nicotine dependence ( 28440896) Night sleep phenotypes ( 27126917) Response to radiotherapy in prostate cancer (toxicity) ( 24974847) Resting heart rate ( 27798624) Restless legs syndrome ( 29029846) Tourette syndrome ( 30818990)
Interacting Genes		31 interacting genes: ABI1 ABI3 AGAP2 AIMP1 BRME1 C1orf116 DBNL DNM3 EFNB2 FAM9A FAT1 FCHSD2 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 PATJ PIAS2 RAD54L2 RASAL3 RYR1 RYR2 SHANK1 SHANK2 STX12 SYCE2 TANC1 TRPC1 ZMYM5	12 interacting genes: ACTB CAMK2A CASK DLG1 DLG4 DLGAP1 GRIA1 GRIN2B HOMER1 INA SHANK1 SPTAN1
Entrez ID		9456	85461
HPRD ID		09211	18146
Ensembl ID		ENSG00000152413	ENSG00000115183
Uniprot IDs		Q5U5K4 Q86YM7	B9EK39 Q9C0D5
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Density Glutamate Receptor Signaling Pathway Regulation Of Cytosolic Calcium Ion Concentration Cell Junction Organization Glutamatergic Synapse Dendritic Spine Monoatomic Ion Channel Activity Synapse Synapse Organization Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Intracellularly Gated Calcium Channel Activity Schaffer Collateral - CA1 Synapse Ligand-gated Ion Channel Signaling Pathway Intracellular Calcium Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Postsynaptic Density Membrane Dendrite Neuron Projection Calcium Ion Homeostasis Postsynaptic Membrane Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration G Protein-coupled Glutamate Receptor Signaling Pathway Cell-cell Signaling Learning Regulation Of Synaptic Transmission, Glutamatergic G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential Ryanodine-sensitive Calcium-release Channel Activity Signaling Calcium-mediated Signaling Cell Communication Calcium Channel Activity Synaptic Receptor Adaptor Activity Ionotropic Glutamate Receptor Signaling Pathway Modulation Of Chemical Synaptic Transmission Associative Learning Synapse Assembly Regulation Of Postsynaptic Membrane Potential Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Calcium-induced Calcium Release Activity Dendritic Shaft Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Actin-based Cell Projection Regulation Of Sequestering Of Calcium Ion Cell Junction Assembly Glutamate-gated Calcium Ion Channel Activity Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum	Postsynaptic Density Modulation Of Chemical Synaptic Transmission Synapse Glutamate Receptor Signaling Pathway Neuron Projection Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Neuron Spine Ligand-gated Ion Channel Signaling Pathway Glutamatergic Synapse Chemical Synaptic Transmission Modulation Of Excitatory Postsynaptic Potential Dendritic Spine Trans-synaptic Signaling Synaptic Signaling Synaptic Membrane Regulation Of Monoatomic Ion Transport Protein Localization To Cell Junction Dendrite Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane Ionotropic Glutamate Receptor Binding Regulation Of Nervous System Process Excitatory Synapse Structural Constituent Of Postsynaptic Density Cell-cell Signaling Regulation Of Transport Signaling Positive Regulation Of Synaptic Transmission Cell Communication Maintenance Of Postsynaptic Density Structure Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Monoatomic Ion Transport Long-term Synaptic Potentiation Regulation Of Membrane Potential Regulation Of Neuronal Synaptic Plasticity Protein Localization To Synapse Cell Junction Cell-cell Junction Regulation Of Synaptic Plasticity Glutamate Receptor Binding Postsynapse Scaffold Protein Binding Postsynaptic Membrane GMP Kinase Activity Glutamate-gated Calcium Ion Channel Activity Endocytic Vesicle Membrane Maintenance Of Postsynaptic Specialization Structure Neuromuscular Junction
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