HOMER1 and C1orf116

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		HOMER1	C1orf116
Gene Name		homer homolog 1 (Drosophila)	chromosome 1 open reading frame 116
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Z Disc Cell Junction Axon Neuronal Cell Body Costamere Dendritic Shaft Apical Part Of Cell Postsynaptic Membrane Excitatory Synapse Neuronal Postsynaptic Density	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Type 5 Metabotropic Glutamate Receptor Binding Protein Complex Scaffold G-protein Coupled Glutamate Receptor Binding Signaling Adaptor Activity Identical Protein Binding Ion Channel Binding Protein Heterodimerization Activity Scaffold Protein Binding	Molecular_function
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Synaptic Transmission Circadian Rhythm Positive Regulation Of Signal Transduction Response To Nicotine Protein Localization To Synapse Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Calcium Ion Import Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity	Biological_process
Pathways
Drugs
Diseases
GWAS		Height ( 18193045) Major depressive disorder ( 20673876)
Protein-Protein Interactions		19 interactors: ABI3 AGAP2 C19orf57 C1orf116 DNM3 EFNB2 FAT1 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 RYR1 RYR2 SHANK1 STX12 TANC1 TRPC1	1 interactors: HOMER1
Entrez ID		9456	79098
HPRD ID		09211	15294
Ensembl ID			ENSG00000182795
Uniprot IDs		Q5U5K4 Q86YM7	Q9BW04
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamate Receptor Signaling Pathway Cell-cell Signaling Cytosolic Calcium Ion Homeostasis G-protein Coupled Glutamate Receptor Signaling Pathway Cellular Calcium Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol Calcium Ion Homeostasis Regulation Of Sequestering Of Calcium Ion Behavior Regulation Of Ion Transport Calcium Ion Transport Into Cytosol Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Transport Regulation Of Ion Homeostasis Cellular Metal Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Synaptic Transmission, Glutamatergic Cellular Cation Homeostasis Calcium Ion Transmembrane Transport Cellular Ion Homeostasis Single-organism Behavior Metal Ion Homeostasis Developmental Process Sarcoplasmic Reticulum Calcium Ion Transport Cellular Response To Caffeine Cellular Chemical Homeostasis Learning Or Memory Ion Homeostasis Cognition Synaptic Transmission Regulation Of Synaptic Transmission Calcium Ion Transport Dendritic Spine Organization Cellular Homeostasis Learning Cell Projection Organization Response To Caffeine Multicellular Organismal Development Anatomical Structure Morphogenesis Ion Transmembrane Transport Anatomical Structure Development Chemical Homeostasis Regulation Of Calcium Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Cellular Response To Alkaloid Positive Regulation Of Ion Transport Synaptic Transmission, Glutamatergic Long-term Memory Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Determination Of Affect	Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Chemical Homeostasis Within A Tissue Behavioral Response To Cocaine Regulation Of Store-operated Calcium Entry G-protein Coupled Glutamate Receptor Signaling Pathway Protein Localization To Synapse Regulation Of Calcium Ion Import Skeletal Muscle Fiber Development Skeletal Muscle Contraction Myotube Cell Development Response To Nicotine Musculoskeletal Movement Response To Cocaine Muscle Fiber Development Myotube Differentiation Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Regulation Of Cation Channel Activity Striated Muscle Contraction Positive Regulation Of Calcium Ion Transport Response To Ammonium Ion Response To Calcium Ion Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Response To Alkaloid Skeletal Muscle Organ Development Striated Muscle Cell Development Adult Behavior Muscle Cell Development Circadian Rhythm Tissue Homeostasis Regulation Of Calcium Ion Transport Positive Regulation Of Ion Transport Muscle Contraction Striated Muscle Cell Differentiation Multicellular Organismal Homeostasis Muscle System Process Muscle Organ Development Rhythmic Process Striated Muscle Tissue Development Muscle Cell Differentiation Response To Metal Ion Muscle Tissue Development Regulation Of Ion Transmembrane Transport Single-organism Behavior Response To Inorganic Substance Muscle Structure Development Synaptic Transmission Behavior
Tagcloud ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1
Tagcloud (Difference) ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1
Tagcloud (Intersection) ?