HOMER3 and HOMER1

Number of citations of the paper that reports this interaction (PMID 9808458)
95

Data Source:
HPRD (in vivo)

		HOMER3	HOMER1
Gene Name		homer homolog 3 (Drosophila)	homer homolog 1 (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Cell Junction Basal Part Of Cell Postsynaptic Membrane Neuronal Postsynaptic Density	Z Disc Cell Junction Axon Neuronal Cell Body Costamere Dendritic Shaft Apical Part Of Cell Postsynaptic Membrane Excitatory Synapse Neuronal Postsynaptic Density
	Molecular Function	Protein Binding Protein C-terminus Binding Protein Domain Specific Binding G-protein Coupled Glutamate Receptor Binding	Type 5 Metabotropic Glutamate Receptor Binding Protein Complex Scaffold G-protein Coupled Glutamate Receptor Binding Signaling Adaptor Activity Identical Protein Binding Ion Channel Binding Protein Heterodimerization Activity Scaffold Protein Binding
	Biological Process	Protein Targeting G-protein Coupled Glutamate Receptor Signaling Pathway Regulation Of Store-operated Calcium Entry	Skeletal Muscle Contraction Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Synaptic Transmission Circadian Rhythm Positive Regulation Of Signal Transduction Response To Nicotine Protein Localization To Synapse Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Calcium Ion Import Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity
Pathways
Drugs
Diseases
GWAS			Height ( 18193045) Major depressive disorder ( 20673876)
Protein-Protein Interactions		28 interactors: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EIF3D FAT1 FRYL GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1	19 interactors: ABI3 AGAP2 C19orf57 C1orf116 DNM3 EFNB2 FAT1 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 RYR1 RYR2 SHANK1 STX12 TANC1 TRPC1
Entrez ID		9454	9456
HPRD ID		07270	09211
Ensembl ID		ENSG00000051128
Uniprot IDs		B2RA10 Q9NSC5	Q5U5K4 Q86YM7
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Cycle Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Gene Expression Regulation Of Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Glutamate Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Signaling Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Regulation Of Mitotic Cell Cycle Positive Regulation Of Ligase Activity Cell Communication DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stimulus Antigen Processing And Presentation Of Peptide Antigen Intracellular Signal Transduction Response To Stimulus Signal Transduction Single-organism Behavior Cell Differentiation Regulation Of Ubiquitin-protein Transferase Activity Movement Of Cell Or Subcellular Component Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic DNA Damage Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Process Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Arrest	Glutamate Receptor Signaling Pathway Cell-cell Signaling Cytosolic Calcium Ion Homeostasis G-protein Coupled Glutamate Receptor Signaling Pathway Cellular Calcium Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol Calcium Ion Homeostasis Regulation Of Sequestering Of Calcium Ion Behavior Regulation Of Ion Transport Calcium Ion Transport Into Cytosol Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Transport Regulation Of Ion Homeostasis Cellular Metal Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Synaptic Transmission, Glutamatergic Cellular Cation Homeostasis Calcium Ion Transmembrane Transport Cellular Ion Homeostasis Single-organism Behavior Metal Ion Homeostasis Developmental Process Sarcoplasmic Reticulum Calcium Ion Transport Cellular Response To Caffeine Cellular Chemical Homeostasis Learning Or Memory Ion Homeostasis Cognition Synaptic Transmission Regulation Of Synaptic Transmission Calcium Ion Transport Dendritic Spine Organization Cellular Homeostasis Learning Cell Projection Organization Response To Caffeine Multicellular Organismal Development Anatomical Structure Morphogenesis Ion Transmembrane Transport Anatomical Structure Development Chemical Homeostasis Regulation Of Calcium Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Cellular Response To Alkaloid Positive Regulation Of Ion Transport Synaptic Transmission, Glutamatergic Long-term Memory Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Determination Of Affect
Tagcloud ?		abetapp alzheimer analyzing assembly coil coiled deposition derivative emphasis evh1 generation herein importantly interacting interaction interacts manipulate metabolism offer plaques players polymerization possibly seems senile serine tail	accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1
Tagcloud (Difference) ?		abetapp alzheimer analyzing assembly coil coiled deposition derivative emphasis evh1 generation herein importantly interacting interaction interacts manipulate metabolism offer plaques players polymerization possibly seems senile serine tail	accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1
Tagcloud (Intersection) ?