MED17 and MED22

Number of citations of the paper that reports this interaction (PMID 12584197)
12

Data Source:
HPRD (in vitro)

		MED17	MED22
Gene Name		mediator complex subunit 17	mediator complex subunit 22
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Membrane Mediator Complex	Cytoplasm Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Transcription Cofactor Activity Transcription Coactivator Activity Receptor Activity Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: BCL6 CTDP1 ESR1 ESR2 HNF4A MED19 MED22 MED29 MED30 MED8 PPARGC1A SMARCA4 SREBF1 SUZ12 TP53 USP49	9 interactors: GOLM1 MED11 MED17 MED27 MED30 MED7 MED8 MED9 THOC7
Entrez ID		9440	6837
HPRD ID		04816	01713
Ensembl ID			ENSG00000148297
Uniprot IDs		Q9NVC6	Q15528
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription DNA-templated Transcription, Initiation Regulation Of Metabolic Process Negative Regulation Of Cell Growth Positive Regulation Of Histone Modification Positive Regulation Of Histone Deacetylation Intracellular Steroid Hormone Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Protein Deacetylation Negative Regulation Of Growth Regulation Of Histone Deacetylation Regulation Of Histone Modification Rhythmic Process Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Growth Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Deacetylation Cellular Response To Lipid Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Chromosome Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Regulation Of Cell Proliferation Cellular Response To Hormone Stimulus Negative Regulation Of Androgen Receptor Signaling Pathway	Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Stem Cell Maintenance Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Stem Cell Development Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Stem Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cell Differentiation Androgen Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Cell Differentiation Intracellular Receptor Signaling Pathway Viral MRNA Export From Host Cell Nucleus Cell Development Cellular Metabolic Process Intracellular Transport Of Virus MRNA Export From Nucleus RNA Export From Nucleus Cell Differentiation
Tagcloud ?		cdk colocalized concentrated connecting eukaryotes excision head helicase hinge holo interacted jaw module modules movable ner nutlin performs pol pulldown switching tbp tfiib tfiie tfiih uv xpb xpg
Tagcloud (Difference) ?		cdk colocalized concentrated connecting eukaryotes excision head helicase hinge holo interacted jaw module modules movable ner nutlin performs pol pulldown switching tbp tfiib tfiie tfiih uv xpb xpg
Tagcloud (Intersection) ?