RECQL4 and PRSS23

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RECQL4	PRSS23
Gene Name		RecQ protein-like 4	protease, serine, 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Membrane	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Bubble DNA Binding ATP Binding Zinc Ion Binding Annealing Helicase Activity ATP-dependent 3'-5' DNA Helicase Activity	Serine-type Endopeptidase Activity
	Biological Process	DNA Strand Renaturation DNA Replication DNA Repair DNA Recombination Multicellular Organismal Development DNA Duplex Unwinding	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ACD EP300 POT1 PRSS23 TERF1 TERF2IP	25 interactors: ACTG1 APP B2M CHP1 EFNA3 FXR1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDDC1 PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		9401	11098
HPRD ID		04805	07149
Ensembl ID		ENSG00000160957	ENSG00000150687
Uniprot IDs		O94761	B4E2J3 O95084
PDB IDs		2KMU
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Regulation Of Telomerase Activity Negative Regulation Of DNA Metabolic Process RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Telomere Assembly Protection From Non-homologous End Joining At Telomere Protein Localization To Chromosome, Telomeric Region Chromosome Organization Positive Regulation Of Telomerase Activity Negative Regulation Of Telomerase Activity Regulation Of DNA Replication Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome DNA Replication Negative Regulation Of Cellular Metabolic Process Regulation Of Organelle Organization DNA Metabolic Process Positive Regulation Of DNA Replication Negative Regulation Of Biosynthetic Process Homeostatic Process Organelle Organization Histone H2B Acetylation Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Negative Regulation Of DNA Recombination At Telomere Segmentation G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Binding Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of DNA Metabolic Process Regulation Of Cellular Component Organization Telomeric Loop Formation Age-dependent Telomere Shortening N-terminal Peptidyl-lysine Acetylation Telomere Formation Via Telomerase Cellular Response To DNA Damage Stimulus Telomere Maintenance Via Telomere Shortening Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response	Platelet Activation Blood Coagulation Hemostasis Cell Differentiation Cellular Component Assembly Regulation Of Body Fluid Levels Organelle Organization Wound Healing Multicellular Organismal Development Generation Of Neurons Cell Activation Dendrite Development System Development Response To Stress Response To Wounding Neurogenesis Mating Behavior Nervous System Development Regulation Of Protein Localization Response To Stimulus Neuron Projection Development Cell Development Developmental Process Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Uncoating Of Virus Mating Anatomical Structure Development Neuron Development Retina Homeostasis Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Protein Targeting To Mitochondrion Protein Complex Assembly Regulation Of Cellular Localization Immune System Process Platelet Degranulation Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity Synaptic Growth At Neuromuscular Junction Active Induction Of Host Immune Response By Virus Mitotic Sister Chromatid Segregation Protein Localization To Mitochondrion Protein Folding Cognition Neuron Projection Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Neuron Differentiation Mitotic Nuclear Division Sister Chromatid Segregation Regulation Of Establishment Of Protein Localization
Tagcloud ?		baller col2a1 conditional copyright craniofacial craniosynostosis cre developmental fl gerold helicases inactivation limb mimicking plate protected prx1 radial rapadilino rescue reserved rights rothmund skeletal thomson transgene trp53
Tagcloud (Difference) ?		baller col2a1 conditional copyright craniofacial craniosynostosis cre developmental fl gerold helicases inactivation limb mimicking plate protected prx1 radial rapadilino rescue reserved rights rothmund skeletal thomson transgene trp53
Tagcloud (Intersection) ?