RAB9A and GDI1

Number of citations: 0 (PubMedID 7744738)
Data Source: HPRD (in vitro)

		RAB9A	GDI1
Name		RAB9A, member RAS oncogene family	GDP dissociation inhibitor 1
Structure			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Melanosome Phagocytic Vesicle Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath Presynaptic Cytosol
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Identical Protein Binding	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Receptor-mediated Endocytosis Protein Transport Rab Protein Signal Transduction Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Exocytosis	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Signal Transduction Small GTPase-mediated Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane Negative Regulation Of Protein Localization
Pathways		Retrograde transport at the Trans-Golgi-Network RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs RHOBTB3 ATPase cycle	RAB GEFs exchange GTP for GDP on RABs
Drugs		Guanosine-5'-Diphosphate	None
Diseases		None	Non-syndromic X-linked mental retardation
GWAS		Red cell distribution width ( 32888494 )	No GWAS studies recorded
Novel Interactors		None recorded	2 novel interactors: IRAK1 PACS1
Interacting Genes		8 interacting genes: BCL3 GDI1 GDI2 PLIN3 RABEPK RHOBTB3 TM9SF2 TRIM14	19 interacting genes: CDC42 EPB41 GNL1 LINC00632 LNX1 OGT PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH RUNX1 TK1 UBQLN4 USP25
Entrez ID		9367	2664
HPRD ID		02236	02114
Ensembl ID		ENSG00000123595	ENSG00000203879
Uniprot IDs		P51151	A0A0S2Z3X8 P31150
PDB IDs		1WMS 7E1T	Not available
GO Terms Enriched among Interactors		Rab GDP-dissociation Inhibitor Activity GDP-dissociation Inhibitor Activity Vesicle-mediated Transport Golgi Apparatus Small GTPase Binding Endosome Membrane Bcl3-Bcl10 Complex Bcl3/NF-kappaB2 Complex Cytoplasm Follicular Dendritic Cell Differentiation Transport Vesicle Trans-Golgi Network Membrane Follicular Dendritic Cell Activation Negative Regulation Of Protein Localization To Cilium Positive Regulation Of Triglyceride Storage Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process	GTPase Activity GTP Binding Myosin V Binding Nucleotide Binding G Protein Activity Regulation Of Vesicle-mediated Transport Hydrolase Activity Regulation Of Proteolysis Intracellular Protein Localization Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Golgi Apparatus Regulation Of Exocytosis GDP Binding Regulation Of Synaptic Vesicle Cycle Immune System Process Endoplasmic Reticulum Membrane Protein-containing Complex Antigen Processing And Presentation Small GTPase-mediated Signal Transduction GTP-dependent Protein Binding Autophagy Cytoplasmic Vesicle Positive Regulation Of Lamellipodium Assembly Protein Localization To Golgi Apparatus Synaptic Vesicle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Myeloid Leukocyte Differentiation Positive Regulation Of Lamellipodium Organization Golgi Membrane Leukocyte Differentiation Regulation Of Lamellipodium Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Core Promoter Binding Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Peptidyl-cysteine Methylation Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Neuron Projection Organization Cortical Cytoskeleton Organization Protein Transport Regulation Of Lamellipodium Organization