RAB9A and RHOBTB3

Number of citations of the paper that reports this interaction (PubMedID 19490898)
48

Data Source:
BioGRID (pull down)

		RAB9A	RHOBTB3
Description		RAB9A, member RAS oncogene family	Rho related BTB domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Melanosome Phagocytic Vesicle Extracellular Exosome	Cytoplasm Golgi Apparatus Cytosol Trans-Golgi Network Membrane Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Identical Protein Binding	Nucleotide Binding GTPase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Small GTPase Binding Ubiquitin Protein Ligase Binding
	Biological Process	Receptor-mediated Endocytosis Protein Transport Rab Protein Signal Transduction Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Exocytosis	Male Gonad Development Regulation Of Proteolysis Retrograde Transport, Endosome To Golgi Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Retrograde transport at the Trans-Golgi-Network RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs RHOBTB3 ATPase cycle	Retrograde transport at the Trans-Golgi-Network RHOBTB3 ATPase cycle
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Red cell distribution width ( 32888494)
Interacting Genes		8 interacting genes: BCL3 GDI1 GDI2 PLIN3 RABEPK RHOBTB3 TM9SF2 TRIM14	18 interacting genes: BHLHE40 CCNE1 CUL3 EFHC2 HGS IHO1 L3MBTL3 PLAGL2 RAB9A RBPMS RBX1 RHOBTB2 RIPPLY3 SNCA TBX15 UBXN11 USP54 VHL
Entrez ID		9367	22836
HPRD ID		02236	09557
Ensembl ID		ENSG00000123595	ENSG00000164292
Uniprot IDs		P51151	O94955
PDB IDs		1WMS 7E1T
Enriched GO Terms of Interacting Partners?		Rab GDP-dissociation Inhibitor Activity GDP-dissociation Inhibitor Activity Vesicle-mediated Transport Golgi Apparatus Small GTPase Binding Endosome Membrane Bcl3-Bcl10 Complex Bcl3/NF-kappaB2 Complex Cytoplasm Follicular Dendritic Cell Differentiation Transport Vesicle Trans-Golgi Network Membrane Follicular Dendritic Cell Activation Negative Regulation Of Protein Localization To Cilium Positive Regulation Of Triglyceride Storage Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process	Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Molecular Adaptor Activity Negative Regulation Of TORC1 Signaling Cul3-RING Ubiquitin Ligase Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of RNA Biosynthetic Process Positive Regulation Of Exocytosis Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cullin-RING Ubiquitin Ligase Complex Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of TORC1 Signaling Negative Regulation Of Autophagy Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process RNA Polymerase II Transcription Initiation Surveillance Renal Sodium Ion Absorption Modification-dependent Protein Catabolic Process Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Renal Sodium Ion Transport Regulation Of Nucleobase-containing Compound Metabolic Process Homologous Chromosome Pairing At Meiosis Regulation Of Transcription By RNA Polymerase II Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Amyloid Fibril Formation Mitotic Cell Cycle Phase Transition Negative Regulation Of Macromolecule Metabolic Process Response To Oxidative Stress Regulation Of TOR Signaling Proteolysis Involved In Protein Catabolic Process Regulation Of Gene Expression Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Nuclear RNA Surveillance Regulation Of Macromolecule Biosynthetic Process Receptor-mediated Endocytosis RNA Surveillance Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity
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