RHOBTB3 and RIPPLY3

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		RHOBTB3	RIPPLY3
Description		Rho related BTB domain containing 3	ripply transcriptional repressor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Trans-Golgi Network Membrane Extracellular Exosome	Nucleus
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Small GTPase Binding Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	Male Gonad Development Regulation Of Proteolysis Retrograde Transport, Endosome To Golgi Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Heart Development Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Embryonic Pattern Specification Pharyngeal System Development
Pathways		Retrograde transport at the Trans-Golgi-Network RHOBTB3 ATPase cycle
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: BHLHE40 CCNE1 CUL3 EFHC2 HGS IHO1 L3MBTL3 PLAGL2 RAB9A RBPMS RBX1 RHOBTB2 RIPPLY3 SNCA TBX15 UBXN11 USP54 VHL	22 interacting genes: CEP76 COMMD1 CRTAP EIF4A1 EIF4A2 HSP90AA1 INCA1 MAP4K4 MCRS1 MLEC ORC2 PIP4P2 PSMB1 RBCK1 RBP4 RGPD6 RHOBTB3 SNRNP70 STXBP1 TIFA TRAF2 WASL
Entrez ID		22836	53820
HPRD ID		09557	10923
Ensembl ID		ENSG00000164292	ENSG00000183145
Uniprot IDs		O94955	P57055
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Molecular Adaptor Activity Negative Regulation Of TORC1 Signaling Cul3-RING Ubiquitin Ligase Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of RNA Biosynthetic Process Positive Regulation Of Exocytosis Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cullin-RING Ubiquitin Ligase Complex Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of TORC1 Signaling Negative Regulation Of Autophagy Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process RNA Polymerase II Transcription Initiation Surveillance Renal Sodium Ion Absorption Modification-dependent Protein Catabolic Process Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Renal Sodium Ion Transport Regulation Of Nucleobase-containing Compound Metabolic Process Homologous Chromosome Pairing At Meiosis Regulation Of Transcription By RNA Polymerase II Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Amyloid Fibril Formation Mitotic Cell Cycle Phase Transition Negative Regulation Of Macromolecule Metabolic Process Response To Oxidative Stress Regulation Of TOR Signaling Proteolysis Involved In Protein Catabolic Process Regulation Of Gene Expression Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Nuclear RNA Surveillance Regulation Of Macromolecule Biosynthetic Process Receptor-mediated Endocytosis RNA Surveillance Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity
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